Situs ambiguous anomaly is a rarely encountered condition in clinical practice that is characterized by the presence of multiple congenital anomalies relevant to intraabdominal organs and the cardiovascular system. While this syndrome is mostly diagnosed as a serious cyanotic cardiac disease in the first year of life, only 5% may survive beyond five years of life, and it can be a diagnostic cha...

Infants of diabetic mothers are significantly at higher risk for major congenital malformations, with cardiovascular anomalies that is the most frequent. In this study, we presented a rare case of dextrocardia and situs inversus totalis (mirror-image dextrocardia) with multiple congenital heart anomalies who was born from a diabetic mother.

Acute aortic dissection is typically seen in the middle aged and elderly population, the majority of the cases are related to systemic hypertension and atherogenic process. In contrast, aortic dissection-related deaths in the young are rare and are mainly associated with genetically based disorders and congenital cardiac anomalies. One of the most recognized congenital risk factors that predisp...

Cervical abnormalities may be congenital or acquired. Congenital anomalies of the cervix are rarely isolated, and more commonly accompany other uterine anomalies. Various imaging tools have been used in the assessment of Mullerian duct anomalies (MDAs). Currently, magnetic resonance imaging (MRI) is the modality of choice for definitive diagnosis and classification of the MDAs. Hysterosalpingog...

Esophageal atresia is often associated with other anomalies. Hereditary and environmental factors may influence the incidence of associated anomalies, particularly of the urogenital system. We had 63 neonates with esophageal atresia admitted to 2 centers in Hamadan, Iran, from 2002 to 2008. They were 38 girls (60.3%) and 25 boy (39.7%). Tracheoesophageal fistula was present in 54 neonates (85.7...

OBJECTIVE To analyze the spectrum of prenatally diagnosed congenital heart disease in a Korean population with 22q11.2 deletion syndrome, and to provide guidelines for screening 22q11.2 deletion prenatally. METHODS This retrospective study evaluated 1,137 consecutive fetuses that had prenatal genetic testing for 22q11.2 deletion because of suspected congenital heart disease between September ...

To assess the quality and appropriateness of Canadian Congenital Anomalies Surveillance System (CCASS), a system based on routine hospital admission/separation records, we compared the congenital anomalies ascertained by CCASS for the period of January 1, 1990 to December 31, 1993 in the province of Alberta with corresponding figures obtained from Alberta Congenital Anomalies Surveillance Syste...

RATIONALE High take-off of the coronary arteries is a rare cardiac anatomic anomaly, which may occur independently or with other congenital heart defects. In the clinical setting, it is noteworthy as a cause of sudden cardiac death. Further, it is vital to identify such anomalies to avoid intraoperative catastrophes in surgeries for congenital heart defects. PATIENT CONCERNS A II/6 systolic h...