نتایج جستجو برای: conjugate addition reaction

تعداد نتایج: 1118710  

2013
Sayantani Das Anandarup Goswami Nagarajan Murali Tewodros Asefa

The Michael reaction, which involves 1,4-addition of a nucleophile (preferably a C-nucleophile) to an a,b-unsaturated compound, offers a simple yet effective way of making C C bonds, which makes it one of the most widely used reactions in both industry and academia. The reaction, as first reported by Arthur Michael in 1887, involves primarily the attack of a Cnucleophile, generated from compoun...

2015
Di Shen Darren L Poole Camilla C Shotton Anne F Kornahrens Mark P Healy Timothy J Donohoe

Reported herein is the use of catalytic [{Ir(cod)Cl}2 ] to facilitate hydrogen-borrowing reactions of ketone enolates with methanol at 65 °C. An oxygen atmosphere accelerates the process, and when combined with the use of a bulky monodentate phosphine ligand, interrupts the catalytic cycle by preventing enone reduction. Subsequent addition of pro-nucleophiles to the reaction mixture allowed a o...

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