1 Jantz MA. The old and the new of sedation for bronchoscopy. Chest 2009; 135:4–6 2 Silvestri GA, Vincent BD, Wahidi MM, et al. A phase 3, randomized, double-blind study to assess the efficacy and safety of fospropofol disodium injection for moderate sedation in patients undergoing flexible bronchoscopy. Chest 2009; 135:41– 47 3 Cohen LB. Clinical trial: a dose-response study of fospropofol dis...

Intraoperative oxygen supplementation to sedated children has been shown to prevent hemoglobin desaturations even in the presence of apnea during pediatric conscious sedation. Although many practitioners deliver supplemental oxygen via a nasal hood, this method is impractical and often unsuccessful if the child is a mouth breather, has moderate adenotonsillar hypertrophy or occasionally cries d...

PURPOSE OF REVIEW The field of interventional bronchoscopy has seen an evolving need for different types of anesthesia for various procedures. This review describes recent advances in the field of anesthesiology that have increased the suitability of conscious sedation under monitored anesthesia care or general anesthesia for prolonged and complex interventional bronchoscopic procedures, especi...

BACKGROUND Mediastinal and hilar lymph node evaluation with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is being performed with increasing frequency. Original reports described performance under general anesthesia. Patient satisfaction is an important determinant of whether EBUS-TBNA may be performed under conscious sedation. METHODS Consecutive patients under...

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children. Intra-articular corticosteroid injection (IASI), one of the cornerstones of treatment for this disease, is usually associated with anxiety and pain. IASI in JIA may be performed under general anesthesia, conscious sedation, or local anesthesia alone. Currently, there is no widely accepted standard of c...

It has been demonstrated that a processed EEG derivative may reflect the patient’s level of consciousness during endoscopic sedation. However, to date a clinical benefit of EEG monitoring with respect to relevant safety parameters in routine gastrointestinal endoscopy has not been demonstrated. During long-lasting procedures (e.g. ERCP, ESD) a propofol-sparing effect has been shown, but a benef...

The use of pulse oximetry in dental procedures involving sedation and children has been encouraged strongly. Reports have indicated that hemoglobin desaturations are not uncommon when a variety of drugs (including nitrous oxide) and dosages are used. The present study investigated the nature of desaturations in relation to patient activity as a function of a drug combination, single drug dose-r...

abstract introduction. some children show aggressive uncontrollable behavior during dental procedures, the only way to control this behavior is pharmacological methods such as conscious sedation. recently intranasal administration of midazolam has been considered. the main goal of our study is to determine the effectiveness of intranasal administration of midazolam (in a does of 0.5 mg/kg) in b...