BACKGROUND Physical activity is associated with improved overall health in those people who survive to older ages, otherwise conceptualised as healthy ageing. Previous studies have examined the effects of mid-life physical activity on healthy ageing, but not the effects of taking up activity later in life. We examined the association between physical activity and healthy ageing over 8 years of ...

In spite of a growing body of research and data, human ageing remains a poorly understood process. Over 10 years ago we developed the Human Ageing Genomic Resources (HAGR), a collection of databases and tools for studying the biology and genetics of ageing. Here, we present HAGR's main functionalities, highlighting new additions and improvements. HAGR consists of six core databases: (i) the Gen...

This essay provides a critical analysis of the ageing-and-innovation discourse. The ageing-and-innovation discourse is a key rhetorical structure that legitimizes very large investments in technologies for older people. In this discourse, ageing is positioned as an imminent crisis that will affect whole societies, both socially and economically. Investing in technological solutions is, in turn,...

background: according to previous studies, most of the speech recognition disorders in older adults are the results of deficits in audibility and auditory temporal resolution. in this paper, the effect of ageing on timecompressed speech and auditory temporal resolution by word recognition in continuous and interrupted noise was studied. methods: a time-compressed speech test (tcst) was conducte...

Scour is one of the main causes bridge failures resulting in significant macro-economic impacts, often beyond direct costs infrastructure damage. Given pressure to increase resilience transport networks, ageing infrastructure, constrained budgets, variable knowledge asset conditions and limited data, mixed ownership operation bridges, concerns about risks climate change, there a need implement ...

The effects of chronic sun exposure on skin are readily apparent when skin not typically exposed to the sun and skin regularly exposed to the sun are compared. While the sun is not the only aetiological factor in the dynamic process of skin ageing, it is the primary exogenous cause among several internal and environmental elements. Thus, photo-ageing, the main focus of this article, is a subset...

INTRODUCTION Population ageing is a welcome testament to improvements in the social, economic and health circumstances over the life course. However, these successes necessitate that we understand more about the pathways of ageing to plan and cost our health and social care services, to support our ageing population to live healthier for longer and to make adequate provisions for retirement. Lo...

Ageing is accompanied by many visible characteristics. Other biological and physiological markers are also well-described e.g. loss of circulating sex hormones and increased inflammatory cytokines. Biomarkers for healthy ageing studies are presently predicated on existing knowledge of ageing traits. The increasing availability of data-intensive methods enables deep-analysis of biological sample...

Ageing is associated with functional, structural and mechanical changes in arteries that closely resemble the vascular alterations in hypertension. Characteristic features of large and small arteries that occur with ageing and during the development of hypertension include endothelial dysfunction, vascular remodelling, inflammation, calcification and increased stiffness. Arterial changes in you...

OBJECTIVE With increasing life expectancy, there is a focus on "healthy ageing". Most activities in this area focus on the elderly. However, the ageing process starts much earlier. Childhood offers an important window to lay a base for future healthy ageing. Thus, to address the full ageing process, we should include younger populations in ageing research. If we aim for healthy ageing across th...