During the fourth week of embryonic development, the rudiment of the respiratory tree appears as a median laryngotracheal groove in the ventral wall of the pharynx. The groove subsequently deepens and its edges fuse to form a septum, thus converting the groove into a splanchnopleuric laryngotracheal tube. This process of fusion commences caudally and extends cranially but does not involve the c...

The crystal structure of the six NH2-terminal zinc fingers of Xenopus laevis transcription factor IIIA (TFIIIA) bound with 31 bp of the 5S rRNA gene promoter has been determined at 3.1 A resolution. Individual zinc fingers are positioned differently in the major groove and across the minor groove of DNA to span the entire length of the duplex. These results show how TFIIIA can recognize several...

For corrugated pipes with a square groove, it is known that there no interaction between the main flow and groove when aspect ratio less than four. When length height are different, occurs in pipe. In previous studies, was investigated whether this dependent on length. However, changing height, shape of vortex generated inside changes, which may cause to occur. Therefore, paper both as well pit...

The iconic helical structure of DNA is stabilized by the solvation environment, where a change in the hydration state can lead to dramatic changes to the DNA structure. X-ray diffraction experiments at cryogenic temperatures have shown crystallographic water molecules in the minor groove of DNA, which has led to the notion of a spine of hydration of DNA. Here, chiral nonlinear vibrational spect...