Abstract Background and Aims To observe the clinical efficacy safety of fractionated plasma separation adsorption integrated with continuous veno-venous hemofiltration (FPSA-CVVH) treatment in patients acute liver failure (ALF). Method In this retrospective study, we enrolled ALF (serum total bilirubin>10mg/dl or Model for End-Stage Liver Disease (MELD) Score>18) hospitalized from...

Voriconazole is a first-line agent for treatment of systemic mycotic infections. However, intravenous use is contraindicated in patients with creatinine clearance <50 ml/minute because of accumulation of the toxic vehicle sulfobutyletherbeta-cyclodextrin sodium [1, 2]. In a recent issue of Critical Care, Kiser and colleagues furnished convincing pharmacological evidence that sulfobutylether-bet...

Objective. To compare complications and survival between the two-site veno-venous versus the veno-venous double lumen extracorporeal membrane oxygenation (ECMO) in infants with respiratory failure. Methods. The Extracorporeal Life Support Organization (ELSO, Ann Arbor, Michigan) provided the registry database, collected between 1999-2009 for this research project. During this period, 9086 infan...

Veno-venous extracorporeal membrane oxygenation (ECMO) for refractory acute respiratory distress syndrome (ARDS) is a rapidly expanding technique. We performed a systematic review and meta-analysis of the most recent literature to analyse complications and hospital mortality associated with this technique. Using the PRISMA guidelines for systematic reviews and meta-analysis, MEDLINE and EMBASE ...