The cerebrovascular effects of graded, controlled dihydralazine-induced hypotension were studied in rats with renal hypertension (RHR) and spontaneous hypertension (SHR). Repeated measurements of cerebral blood flow (CBF) were made using the intraarterial 133Xenon injection technique in anaesthetised normocapnic animals. Dihydralazine was administered in single increasing i.v. doses (0.1 to 2 m...

Abstract Background In order to apply the findings of antihypertensive randomised controlled trials older adults, it is important understand populations included and consider generalizability results cohorts that may have been excluded. The purpose this study was determine whether participants with orthostatic hypotension were in trial therapy adverse event rates particular importance cohort; n...

Hip fractures are a common pathology among patients older 50 years and cause disability, reduced duration quality of life, even with adequate management surgery. In the perioperative period, most complications leading to death cardiovascular disease. about hip fracture.
 The aim our study was determine safest method anesthesia in context acute myocardial injury during fracture objectives w...

Introduction: Sacubitril-valsartan is a recently approved drug. However, there are few data regarding safety issues. We aimed to summarize the available evidence sacubitril-valsartan’s and tolerability.Methods: conducted systematic review with meta-analysis of randomized controlled trials (RCTs) enrolling patients receiving sacubitril-valsartan for any condition, compared standard therapy or pl...

Soak feet with warm water is a combined therapy method of thermotherapy and hydrotherapy that works to release istamine bradykinin. The bradykinin causes vasodilation blood vessels. purpose the study: identify effect soaking on lowering pressure. Method:This research quantitative systematic review method. design used was Randomized Controlled Trials (RCT) 9 studies.Results:Obtained from studies...

BACKGROUND: Cesarean section (C-section) is the most frequently performed surgery in obstetrics, generally using subarachnoid block (SAB) or epidural for anesthesia. The previous studies have shown effectiveness of fluid loading and vasopressor pretreatment preventing maternal hypotension (decreased blood pressure), common side effect SAB. However, timing response to these treatments has not be...

During the last decade, two angiotensin converting enzyme (ACE) inhibitors, captopril and enalapril, have become accepted into clinical practice and are regarded as effective treatments for hypertension and congestive cardiac failure.' A third agent, lisinopril, had recently become available and others are likely to be introduced in the near future. It is clear, therefore, that more patients, w...