Eugene Varfolomeev,1 John W. Blankenship,1 Sarah M. Wayson,1 Anna V. Fedorova,1 Nobuhiko Kayagaki,2 Parie Garg,2 Kerry Zobel,1 Jasmin N. Dynek,1 Linda O. Elliott,3 Heidi J.A. Wallweber,1 John A. Flygare,3 Wayne J. Fairbrother,1 Kurt Deshayes,1 Vishva M. Dixit,2,* and Domagoj Vucic1,* 1Department of Protein Engineering 2Department of Physiological Chemistry 3Department of Medicinal Chemistry Gen...

The metal ion chemistry of macrocyclic ligands has now become a major subdivision of inorganic chemistry and is a growing area of research in inorganic and bioinorganic chemistry. The field of macrocylic chemistry of metals is developing very fast because of its applications and importance in the area of coordination chemistry. Macrocyclic ligands and their transition metal complexes have recei...

The Cu(I)-catalyzed azide-alkyne cycloaddition reaction, also known as click chemistry, has become a useful tool for the facile formation of 1,2,3-triazoles. Specifically, the utility of this reaction has been demonstrated by the synthesis of structurally diverse bi- and bis-1,2,3-triazoles. The present review focuses on the synthesis of such bi- and bistriazoles and the importance of using cop...

Pyochelin (PCH) is a siderophore (extracellular chelator) produced by the pathogenic bacterium Pseudomonas aeruginosa (PAO). PCH is implicated in iron (Fe3+) transport to PAO, and is crucial for its metabolism and pathogenicity. Due to the chemical similarity with Fe3+, gallium (Ga3+) interferes with vital iron-dependent processes in bacterial cells, thereby opening new perspectives for the des...

The coordination chemistry of chiral NHC-oxazoline bidentate ligands was investigated with silver(I) and gold(I), yielding stable dinuclear cationic complexes in good yields via N-coordination the oxazoline heterocycle. After full characterization these complexes, reactivity homogeneous catalysis under oxidative conditions studied.

coordination chemistry is currently of great interest in research. The use of transition-metal centers and coordination chemistry for directing the formation of complex structures has evolved into one of the most widely used strategies for organizing molecular building blocks into supramolecular arrays.1–3 Assembling extended supramolecular architectures by selecting the chemical structure of o...