background : the role of minerals on parasite persistency and the interaction between minerals and animal responses to the parasite infestation is not clear. for these reasons, the present re­search was aimed to compare copper, zinc and iron status in sheep with parasitic myocarditis and healthy ones in 2009. methods : blood and heart tissue samples were collected from 145 slaughtered sheep and...

PURPOSE Tetrathiomolybdate (TM), a copper-lowering agent, has been shown in preclinical murine tumor models to be antiangiogenic. We evaluated the antitumor activity of TM in patients with advanced kidney cancer in a Phase II trial. EXPERIMENTAL DESIGN Fifteen patients with advanced kidney cancer were eligible to participate in this trial. TM was initiated p.o. at 40 mg three times a day with...

Background: One of the most critical problems in the field of water and food pollution is the heavy metal pollution. Agricultural products are exposed to this type of contamination through wastewater; industrial activity and population pollutions are also in its area. Since the plant in the affected areas can directly enter heavy metals into the food chain, so, it is important to check their le...

The electromigration-induced failure in flip-chip eutectic SnPb solder joints with a 10m-thick Cu under-bump metallization (UBM) was studied without the effect of current crowding in the solder region. The current crowding occurred inside the UBM instead of in the solder joint at the current density of 3.0 × 10 A/cm because of the spreading of current in the very thick Cu UBM. In these joints, ...

Five 28- to 33-d experiments involving 460 crossbred pigs weaned at 28 +/- 2 d of age (initial weight, 6.7 to 8.1 kg) were conducted to determine the effects of feeding high dietary levels of Cu sulfate (CuSO4) or Cu oxide (CuO) on rate and efficiency of gain and liver Cu stores of weanling pigs. The pigs were housed in groups of five to six/pen and fed a fortified, unmedicated, corn-soybean me...

this study investigated the cytochemical responses in hediste diversicolor exposed to the environmental concentrations of cadmium (1µm cd), copper (1µm cu) and to their equimolar mixture for 48h. lysosomal membrane stability (lms), neutral lipids (nl) level, lipofuscin (lf) content and ca2+-atpase activity were determined as early subcellular biomarkers of toxicity. the biomarker battery pointe...

chronic hepatitis b virus (hbv) infection is a major liver disease worldwide and its clinical manifestations are linked to immune response. the purpose of this study was to evaluate the relationship between selenium, copper, and zinc in comparison with transaminase level in chronic hbv patients. serum samples of the hbv infected patients were obtained from tooba medical center, sari, iran. sixt...

In this study, the effect of various doses of ouabain (1, 2, and 5 mg/kg, i.p.) on weight and flow rate of submandibular gland (SMG) and changes in zinc and copper levels in pure saliva and serum of rats was investigated. The time interval between injection of drug and sampling was 30 min. In addition, the effect of a single and toxic dose of ouabain (5 mg/kg, i.p.) in various time intervals (3...