Gram-negative endotoxins have been implicated in the pathogenesis of equine CHO laminitis, bovine coliform mastitis, and adult and neonatal septicemias. Fortuitously, the demonstration that cattle and horses could be protected from various Gram-negative endotoxins via anti-core-antigen antibodies offers viable possibilities for immunologically protecting animals from the deadly effects of endot...

Hepatitis B virus core antigen (HBcAg) plays a critical role in terminating acute Hepatitis B virus infection and may be used as a potential vaccine candidate. The cell surface major histocompatibility complex (MHC) class 1 molecules are thought to be involved in the presentation of HBcAg. Surface MHC class 1 HLA A2 heavy chain (HC) and trimeric molecules were characterized on transfected Hela ...

background: hydatidosis is one of the cosmopolitan parasitic zoonoses caused by the larval stage of echinococcus granulosus. diagnosis of hydatidosis is still an unresolved problem. serological tests using crude antigens for diagnosis of e. granulosus are sensi-tive, however their specificity are not satisfactory. therefore, who recommended spe-cific serological methods using specific antigens,...

In order to estimate the prevalence of serological markers of exposure to Hepatitis B Virus (HBV), 295 subjects were selected at random from the National Registry of human immunodeficiency virus positive subjects. Evidence of exposure to HBV was defined as: testing Hepatitis B surface antigen (HBsAg) and anti-Hepatitis B core antigen (anti-HBc) positive or anti-HBc positive only. Overall, 133 (...

The murine monoclonal antibody (MAb) DF3 was prepared against a human breast carcinoma. Previous studies have demonstrated that DF3 antigen levels are elevated in plasma of patients with breast cancer. Furthermore, MAb DF3 reacts with circulating glycoproteins of different molecular weights ranging from approximately 300 to 450 kd. The present study demonstrates that plasma DF3 antigen is compr...

objective(s): the aim of this study was to estimate effects of hyperbaric (hb) treatment by determination of cd15s and cd11b leukocyte proinflammatory markers expression.  in addition, this study describes changes in cd77 and cd34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. materials and methods:expression of cd11b and cd...

capture elisa system was developed for diagnosis of visceral leishmaniasis (vl) using a monoclonal antibody raised against an antigen previously detected in the urine of vl patients. urine samples from confirmed vl cases from yemen, nepal, spain, sudan and brazil were tested in the capture elisa in comparison with urine samples from endemic and non-endemic areas along with urine samples from pa...

Pseudomonas aeruginosa lipopolysaccharide (LPS) contains two glycoforms of core oligosaccharide (OS); one form is capped with O antigen through an alpha-1,3-linked L-rhamnose (L-Rha), while the other is uncapped and contains an alpha-1,6-linked L-Rha. Two genes in strain PAO1, wapR (PA5000) and migA (PA0705), encode putative glycosyltransferases associated with core biosynthesis. We propose tha...

Helicobacter pylori NCTC 11637 lipopolysaccharide (LPS) expresses the human blood group antigen Lewis x (Le(x)) in a polymeric form. Le(x) is beta-D-galactose-(1-4)-[alpha-L-fucose-(1-3)]-beta-D-acetylglucosamine. Schematically the LPS structure is (Le(x))n-core-lipid A. In this report, we show that Le(x) expression is not a stable trait but that LPS displays a high frequency (0.2 to 0.5%) of p...

we developed an immunogen to stimulate multivalent immunity against hepatitis b surface antigen (hbsag) and hepatitis b core antigens (hbcag). immune responses specific for both hbsag and hbcag play an important role in controlling the infection. hbsag-specific antibodies mediate elimination of virions at an early stage of infection and prevent the spread of virus. the immunogen was constructed...