a comprehensive evaluation of the residual levels of organochlorine insecticides (ocis) in the sediment cores of cochin estuarine system (ces) is highlighted in this research article. it assessed the distribution pattern and impact of these xenobiotics in this environmental niche. fifteen persistent organochlorine compounds (ocs) were quantitatively analysed in the six sediment core samples col...

this paper reports the synthesis of polypyrrole coated sno2/znoelectrospunnanofibers via vapor phase polymerization method. in order to prepare one dimensional (sno2-zno)/polypyrrole with the core sheath structure, first sno2-zno composite nanofibers were synthesized via electrospinning method followed by adsorption of fe3+ on the surface of the sno2-zno nanofibers and finally pyrrole was polym...

Hepatitis C virus (HCV) encodes two envelope glycoproteins, E1 and E2. Their structure and mode of fusion remain unknown, and so does the virion architecture. The organization of the HCV envelope shell in particular is subject to discussion as it incorporates or associates with host-derived lipoproteins, to an extent that the biophysical properties of the virion resemble more very-low-density l...

The three variable regions of hepatitis C virus (HCV) glycoprotein E2 can be removed simultaneously from the E2 ectodomain (residues 384-661) without affecting folding or CD81 binding. In this study, we show that deletion of hypervariable region (HVR) 2 or the intergenotypic variable region (igVR) in the context of the E1E2 polyprotein eliminates formation of heterodimers, reduces CD81 binding ...

Various strategies involving the use of hepatitis C virus (HCV) E1 and E2 envelope glycoproteins as immunogens have been developed for prophylactic vaccination against HCV. However, the ideal mode of processing and presenting these immunogens for effective vaccination has yet to be determined. We used our recently described vaccine candidate based on full-length HCV E1 or E2 glycoproteins fused...

in this research controlled coating of magnetite (fe3o4) nanoparticles with sio2 was investigated. the fe3o4 nanoparticles were synthesized via chemical co-precipitation and then coated by silica according to stober method. effects of tetra ethyl ortho silicate (teos) concentration and ethanol to teos on the coating thickness were investigated. x-ray powder diffraction, fourier transform infrar...

in this study the effect of a methylated derivative of nitrogen mustard (mechloroethamin) on solubilized and reconstituted chromatin was investigated using uvnis spectroscopy, dna and sds gel electrophoresis and densitomeoic scanning techniques, the results indicated that the 210 and 260 nm absorbances of reconstituted chromatin were decreased in a dose-dependent manner after treatment with var...