Mahelkova et al. recently published an interesting study evaluating the corneal structures in buphthalmic eyes and healthy eyes in patients with unilateral congenital glaucoma by using confocal microscopy. The authors reported statistically significant increase of the basal epithelial cell density and significant reduction of the endothelial cell density in the buphthalmic eyes, whereas the dif...

OBJECTIVE To evaluate Descemet membrane endothelial keratoplasty for management of corneal endothelial disorders. METHODS Descemet membrane endothelial keratoplasty was performed in 200 patients with Fuchs endothelial dystrophy or bullous keratopathy. Best-corrected visual acuity, subjective and objective refractive outcome and stability, and endothelial cell density were evaluated at 1, 3, a...

Following the application of needle, intraocular lens, freeze, and laser wounds to the center of discrete 1 cm2 areas, density-limited monolayers of cultured rabbit corneal endothelium demonstrate wound healing responses similar to those seen in in vivo corneas. The wounded monolayer reforms in a time period consistent with that seen in both in vivo and in vitro organ culture models, thus sugge...

AIM To describe and compare the corneal endothelial cell density and morphology in young, low and moderate myopic Chinese adults in Malaysian Chinese population. METHODS Non-contact specular microscopy (Topcon SP3000P, Tokyo, Japan) was performed in low (n=78; 21.22±1.51 years) and moderate (n=78; 21.82±1.40 years) myopic subjects. The mean of three consecutive measurements of endothelial cel...

Introduction: Cataract is the leading cause of treatable blindness worldwide. Phacoemulsification with intraocular lens (IOL) implantation most common surgical procedure performed for treatment cataract. The diabetic cornea has decreased corneal endothelial cell density (CED) due to dysfunction and malfunctioning repair systems. Objective: To compare mean before after phacoemulsification in pat...

In these experiments, the binding of 3H . ouabain, a specific inhibitor of Na/K ATPase, was used to quantitate the density of Na/K ATPase pump sites in the rabbit corneal endothelium. The uptake of ouabain by the corneal endothelium shows two components: one that saturates at a ouabain concentration near 2 X 10(-7) M (specific binding), and one component that increases linearly with increasing ...

PURPOSE Boston Terriers (BTs) have a greater prevalence of corneal endothelial dystrophy (CED), in comparison to other canine breeds. Similar to Fuchs' endothelial corneal dystrophy (FECD), this condition is characterized by endothelial cell degeneration with secondary corneal edema. This study assessed corneal morphology using in vivo confocal microscopy (IVCM) and Fourier-domain optical coher...