S-1. Association of coronary artery vitamin D receptor expression and Systemic Risk Factors for Coronary Artery Atherosclerosis Ran Xie, M.D., Ph.D.1, Xuezhi Jiang, MD1, David M. O’Sullivan, PhD1, Peter F. Schnatz, D.O.1,2. 1ObGyn & Internal Medicine, The Reading Hospital and Medical Center, Reading, PA; 2ObGyn & Internal Medicine, Jefferson Medical College of Thomas Jefferson University, Phila...

familial hypercholesterolemia (fh) is a hereditary dislipidemia. patients present with extremely high level of low-density lipoprotein cholesterol (ldl-c), which is due to mutation in the gene of ldl receptor. homozygous patients (hofh) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. in homozygous individuals cardiovasc...

Background. To determine whether or not a moderate genetic defect of homocysteine metabolism is associated with the development of coronary artery disease, we studied the prevalence of thermolabile methylenetetrahydrofolate reductase, which is probably the most common genetic defect of homocysteine metabolism. Methods and Results. Three hundred thirty-nine subjects who underwent coronary angiog...

How Is Coronary Artery Disease Treated? Coronary artery disease can be stabilized and treated through healthy living and the use of medications to control risk factors and symptoms. In some patients, the coronary arteries become more severely blocked and require a revascularization procedure. The 2 procedures to manage a blocked coronary artery are to implant a stent in the area of the blockage...

introduction: although coronary endarterectomy is not an ideal procedure, it is the only available option for cardiac surgeons in some patients with diffuse coronary artery disease. based on the majority of conducted studies, the results of coronary endarterectomy (including survival, graft patency, and recurrence of the symptoms of myocardial ischemia) are less prevalent than standard coronary...

background according to the increase of patients with coronary artery disease, paying more attention to the quality of life seems to be important. one of the factors affecting the quality of life is spiritual health. spiritual health as one of the main aspects of health is usually ignored. objectives the current study was performed to determine the relationship between spiritual health and qual...

Background The widespread availability of the coronary artery calcium scan to diagnose coronary artery atheroma semiquantitatively and its prognostic significance has frequently resulted in a difficult therapeutic decision for physicians caring for asymptomatic patients. Patients and Risk Factors Of particular concern are patients over 40 years of age and young adults characterized by multipl...

Transplant-associated coronary artery disease (TxCAD), or coronary vasculopathy, is the leading cause of death after the first year of transplantation and, once diagnosed, is associated with a mortality rate of 40% at two years (1). Though coronary vasculopathy is widely believed to represent some form of chronic humoral and cellular rejection, some nonimmune risk factors such as older donor ag...

BACKGROUND Most studies of coronary artery involvement and associated risk factors in Kawasaki disease have used the Japanese Ministry of Health dichotomous criteria. Analysis of serial normalized artery measurements may reveal a broader continuous spectrum of involvement and different risk factors. METHODS AND RESULTS Clinical, laboratory, and echocardiographic measurements obtained at basel...

OBJECTIVES The purpose of our study was to assess the prevalence and extent of coronary artery atherosclerosis in asymptomatic patients with vascular erectile dysfunction (ED). BACKGROUND An association between ED and ischemic heart disease has been suggested, but it is unknown if it represents a marker of subclinical coronary atherosclerosis. METHODS We studied 70 consecutive patients with...