Transient dynamics is pervasive in the human brain and poses challenging problems both in mathematical tractability and clinical observability. We investigate statistical properties of transient cortical wave patterns with characteristic forms (shape, size, duration) in a canonical reaction-diffusion model with mean field inhibition. The patterns are formed by ghost behavior near a saddle-node ...

The distribution of voltage-dependent calcium channels in kidney pre- and postglomerular resistance vessels was determined at the molecular and functional levels. Reverse transcription-polymerase chain reaction analysis of microdissected rat preglomerular vessels and cultured smooth muscle cells showed coexpression of mRNAs for T-type subunits (Ca(V)3.1, Ca(V)3.2) and for an L-type subunit (Ca(...

During embryonic development, young neurons migrate from the ventricular zone to the cortical plate of the cerebral cortex. Disturbances in this neuronal migration have been associated with numerous diseases such as mental retardation, double cortex, Down syndrome, and epilepsy. One possible cause of these neuropathologies is an aberration in normal gap junctional communication. At least 20 con...

OBJECTIVE The aim of the study was to investigate the effects of aging on human cortical auditory processing of rising-intensity sinusoids and speech sounds. We also aimed to evaluate the suitability of a recently discovered transient brain response for applied research. METHODS In young and aged adults, magnetic fields produced by cortical activity elicited by a 570-Hz pure-tone and a speech...

Neurons are often connected, spatially and temporally, in phenomenal ways that promote wave propagation. Therefore, it is essential to analyze the emergent spatiotemporal patterns understand working mechanism of brain activity, especially cortical areas. Here, we present an explicit mathematical analysis, corroborated by numerical results, identify investigate spatiotemporal, non-uniform, emerg...

Purpose: In this study, the main goal was to determine the correlation between the thickness of cerebral cortex and the severity of cognitive disorder in Alzheimer's disease Materials and method: Twenty patients diagnosed with Alzheimer’s disease with mean age of 72.95 year(14 women and 6 men) and Ten Cognitively normal (CN) subjects with mean age of 70.50 year( 7 women and 3 men) were include...

We have used an antibody against the ryanodine receptor/calcium release channel of skeletal muscle sarcoplasmic reticulum to localize a calcium release channel in sea urchin eggs. The calcium release channel is present in less than 20% of immature oocytes, where it does not demonstrate a specific cytoplasmic localization, while it is confined to the cortex of all mature eggs examined. This is i...

At extracellular pH values close to their pKa values the weak bases, ammonia and procaine, elicited a series of events in non-activated Xenopus eggs, some of which resembled those normally occurring at fertilization. These included: (1) a transient increase in membrane conductance; (2) modification of the microvilli; (3) thickening of the cortical cytoplasm and displacement of the cortical gran...

The excitability of the motor cortex is modulated before and after voluntary movements. Transcranial magnetic stimulation studies showed increased corticospinal excitability from about 80 and 100 ms before EMG onset for simple reaction time and self-paced movements, respectively. Following voluntary movements, there are two phases of increased corticospinal excitability from 0 to approximately ...