introduction: in recent years, a few studies have been conducted in the area of the cost-effectiveness of the eplerenone; it's notable that coherent and clear evidence are not available. therefore, this study aimed to systematically review studies of cost-effectiveness of eplerenone in the treatment of cardio-vascular patients. methods: this systematic review study was conducted in 2016. t...

Domain-specific modeling promises to increase productivity by offering modeling languages tailored to a problem domain. Such modeling languages are typically defined by a metamodel. In consequence of changing requirements and technological progress, the problem domains and thus the metamodels are subject to change. Manually migrating models to a new version of their corresponding metamodel is c...

HPV vaccine has been recently added to the Iran Drug List, so decision makers need information beyond that available from RCTs to recommend funding for this vaccination. Modeling and economic studies have addressed some of those information needs. We reviewed cost effectiveness studies to find a suitable model for Iranian population to determine the potential cost effectiveness of HPV vaccine p...