manufacturing new hepatitis b virus vaccines, specifically by the use of nanoparticles, is of high global interest. in this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis b virus’ surface antigen (hbsag) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. the physicochemical properties of the conjugate were characteri...

this paper has revised the combined model of chan & qi with supply chain operations reference (scor) .this combined model with hierarchical structure, has three levels and seven criteria that some criteria are quantitative (cost, use of source) and others of them are qualitative (quality, flexibility, tangible, validity and innovation). in order to improvement of this model, this paper has comb...

the existing works considering the flow-based discount factor in the hub and spoke problems, assume that increasing the amount of flow passing through each edge of network continuously decreases the unit flow transportation cost. although a higher volume of flow allows for using wider links and consequently cheaper transportation, but the unit of flow enjoys more discounts, quite like replacing...

General cost for CNC machining and the associated energy cost are set in the context of making economic and environmental improvements. This creates an incentive for manufacturing companies to investigate the energy efficiency of manufacturing processes. The paper presents a costing model, based on machining experiments. The model is accompanied with an industry based case to estimate the cost ...

magnetic levitation (maglev) is amongst the most advanced technologies that are available to the transportation industries. it has already been noticed by decision makers in many countries around the globe. contrary to such high levels of interest, there are no practical algorithms available to the engineers and/or managers to assist them in analyzing economics of the maglev systems. therefore,...

In this research, a model for optimal PM planning based on reliability is developed and solved for multi-component systems. In the proposed model, the type of PM actions for each inspection period is determined in such manner that the total weighted related costs are minimized while a minimum required system reliability is maintained. The planning horizon is divided into some inspections interv...