نتایج جستجو برای: cox i

تعداد نتایج: 1084140  

Journal: :Cancer research 2000
I Shureiqi D Chen R Lotan P Yang R A Newman S M Fischer S M Lippman

We previously found (I. Shureiqi et al., Carcinogenesis (Lond.), 20: 1985-1995, 1999; I. Shureiqi et al, J. Natl. Cancer Inst., 92: 1136-1142, 2000) that (a) 15-lipoxygenase-1 (15-LOX-1) protein and its product 13-S-hydroxyoctadecadienoic acid (13-S-HODE) are decreased; and (b) nonsteroidal anti-inflammatory drug (NSAID)-induced 15-LOX-1 expression is critical to NSAID-induced apoptosis in colo...

Journal: :Journal of Korean Medical Science 2002
Sang Hyun Kim Hyung Jun Chu Dae Hwan Kang Geun Am Song Mong Cho Ung Suk Yang Hyon Jeen Kim Hae Young Chung

The involvement of NF-kappa B binding activity is known to be important in the mechanism of acute liver injury and in the induction of cyclooxygenase (COX-2). This study was performed to evaluate NF-kappa B binding activity and the expression of COX-2 in chronic liver injury induced by carbon tetrachloride (CCl(4)). Liver tissues from Sprague-Dawley rats were collected at 1, 3, 5, and 7th week ...

Journal: :iranian red crescent medical journal 0
hoda noorkojuri department of biostatistics, faculty of medical sciences,tarbiat modares university, tarbiat modares university, tehran, ir iran ebrahim hajizadeh department of biostatistics, faculty of medical sciences,tarbiat modares university, tarbiat modares university, tehran, ir iran; tarbiat modares university, jalal ale ahmad highway, tehran, ir iran, tel: +98-2182883810, fax: +98-2182884555 ahmadreza baghestani 2. department of biostatistics, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, ir iran mohamadamin pourhoseingholi department of biostatistics, gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran

conclusions the use of smoothing methods helps us to eliminate non-linear effects but it is more appropriate to use cox proportional hazards model in medical data because of its’ ease of interpretation and capability of modeling both continuous and discrete covariates. also, cox proportional hazards model and smoothing methods analysis identified that age at diagnosis and tumor size were indepe...

Journal: :Journal of geomagnetism and geoelectricity 1988

Journal: :iranian journal of pharmaceutical research 0
afshin zarghi shahid beheshti univ. med. sci. iman sabakhi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences vigen topuzyan the scientific thechnological centre of organic and pharmaceutical chemistry nasraal. mnjoyan institute of fine organic chemistry, yerevan, armenia. zahra hajimahdi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences bahram daraei department of toxicology, faculty of medical sciences, tarbiat modares university hadi arefi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

as a continuous research for discovery of new cox-2 inhibitors, chemical synthesis, in vitro biological activity and molecular docking study of anew group of 1,4-dihydropyridine (dhp) derivatives were presented. novel synthesized compounds possessing a cox-2 so2me pharmacophore at the para position of c-4 phenyl ring, different hydrophobic groups (r1) at c-2 position and alkoxycarbonyl groups (...

Journal: :The Annals of Iowa 1906

Journal: :ICES Journal of Marine Science 1968

Journal: :Communications in Statistics - Theory and Methods 2003

Journal: :Mathematics of Computation 2015

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