OBJECTIVES We sought to examine the short-term and longer term (6-week) effects of continuous positive airway pressure (CPAP) on myocardial energetics. BACKGROUND Obstructive sleep apnea (OSA) and heart failure (HF) are both states of increased afterload and metabolic demand. Treatment with CPAP may initially reduce stroke volume but subsequently improves left ventricular function. However, i...

RATIONALE Continuous positive airway pressure (CPAP) and mandibular advancement device (MAD) therapy are commonly used to treat obstructive sleep apnea (OSA). Differences in efficacy and compliance of these treatments are likely to influence improvements in health outcomes. OBJECTIVES To compare health effects after 1 month of optimal CPAP and MAD therapy in OSA. METHODS In this randomized ...

BACKGROUND Obstructive sleep apnoea (OSA) is a common and potentially reversible cause of systemic hypertension. The mechanisms whereby OSA leads to hypertension and the effects of treatment on arterial function, however, are not well established. Microvascular arterial endothelial and smooth muscle function was assessed in subjects with OSA before and after treatment with continuous positive a...

Some patients with obstructive sleep apnoea syndrome (OSAS; respiratory distress index (RDI) of >5 events.h(-1)) experience residual excessive daytime subjective sleepiness (Epworth Sleepiness Scale (ESS) score of >10), despite adequate use of continuous positive airway pressure (CPAP) therapy. The aim of the present study was to identify clinical and polysomnographic predictors of this sleepin...

OBJECTIVE This study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure and acoustic stapedial reflex and the correlation between CPAP and middle ear pressure. STUDY DESIGN Prospective cohort study. SETTING Tertiary hospitals. SUBJECTS AND METHODS Fifty patients with obstructive sleep apnea-hypopnea syndrome were assigned to the study group, and ...

BACKGROUND Decreased cerebral glucose metabolism has been reported in patients with sleep apnea syndrome (SAS), but it has yet to be decided whether cerebral glucose metabolism in SAS can be altered by continuous positive airway pressure (CPAP) treatment. OBJECTIVE The aim of this study was to evaluate cerebral glucose metabolism changes in patients with SAS after CPAP treatment. METHODS Th...

Continuous positive airway pressure (CPAP) is a safe therapy for the management of obstructive sleep apnea (OSA). Complications such as sinus infection, bronchitis, ear pain, nasal congestion, and dryness of mucous membranes secondary to CPAP use have been reported. To follow, we describe a rare case of alternobaric vertigo secondary to CPAP therapy. To date, there has been only one reported ca...

Nasal continuous positive airway pressure (CPAP) is a noninvasive form of respiratory assistance that has been used to support spontaneously breathing infants with lung disease for nearly 40 years. Following reports that mechanical ventilation contributes to pulmonary growth arrest and the development of chronic lung disease, there is a renewed interest in using CPAP as the prevailing method fo...

STUDY OBJECTIVES To evaluate the effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure (CPAP). DESIGN A randomized, crossover design was employed. SETTING The study was conducted at two suburban community-based hospital sleep laboratories. PATIENTS Data were collected on 38 obstructive sleep apnea patients (mean age, 4...

Background—Many patients with sleep apnoea/hypopnoea syndrome (SAHS) find nasal continuous positive airway pressure (CPAP) treatment unsatisfactory due to side eVects related to mouth air leakage. A study was performed to compare side eVects with face mask and nose mask CPAP therapy in patients with SAHS, with and without uvulopalatopharyngoplasty (U3P). Methods—Twenty newly diagnosed patients ...