OBJECTIVES The objective of the current study was to quantify the effects of the strength of US state graduated driver licensing laws and specific licensing components on the rate of teenage driver fatal crash involvements per 100,000 teenagers during 1996-2007. The strengths of state laws were rated good, fair, marginal, or poor based on a system developed previously by the Insurance Institute...

As advanced technologies in wafer manufacturing push patterning processes toward lower-k1 subwavelength printing, lithography for mass production potentially suffers from decreased patterning fidelity. This results in generation of many hotspots, which are actual device patterns with relatively large CD and image errors with respect to on-wafer targets. Hotspots can be formed under a variety of...

Overall comparisons of crash rates based on mileage indicate that truck crash rates are lower than car crash rates, but that truck crashes are more severe. In 1978 the overall U.S. crash rate for cars was estimated at 8.2 accidents per million vehicle-miles of travel; for large trucks (including combinations) the rate was 4.7 per million vehicle-miles, and for combination trucks (e.g., tractor-...

India accounts for the world’s greatest concentration of coal fires which cause several devastating environmental effects. Only Jharia Coal Field (JCF) in Jharkhand (India) contains nearly half of subsurface mine fires (hotspots) in Indian coalfields. Therefore attention is required in this direction for mapping, monitoring and detecting these hotspots. Operational satellite images can be very ...

Protein-protein interactions, a key to almost any biological process, are mediated by molecular mechanisms that are not entirely clear. The study of these mechanisms often focuses on all residues at protein-protein interfaces. However, only a small subset of all interface residues is actually essential for recognition or binding. Commonly referred to as "hotspots," these essential residues are ...

Recombination is the main cause of genetic diversity. Thus, errors in this process can lead to chromosomal abnormalities. Recombination events are confined to narrow chromosome regions called hotspots in which characteristic DNA motifs are found. Genomic analyses have shown that both recombination hotspots and DNA motifs are distributed unevenly along human chromosomes and are much more frequen...

Among mammals, genetic recombination occurs at highly delimited sites known as recombination hotspots. They are typically 1-2 kb long and vary as much as a 1,000-fold or more in recombination activity. Although much is known about the molecular details of the recombination process itself, the factors determining the location and relative activity of hotspots are poorly understood. To further ou...

This paper presents a driver performance map of braking and steering in response to three driving scenarios that lead to rear-end crashes. This map encompasses low risk, conflict, near-crash, and crash imminent driving states that correspond to advisory warning, crash imminent warning, and crash mitigation functionalities for intelligent vehicle rear-end crash countermeasures. Specifically, thi...