real coded genetic algorithm, rcga, is the type of ga which operates on chromosomes with real valued parameters. different mutation and crossover operations are defined for rcga. one usable crossover for this kind of ga is to consider its chromosomes simply as bit strings and utilize the same operations as binary coded ga. in this paper, we attempt to show that this kind of crossover can not ha...

this study was designed to elucidate the effect of ascorbic acid on salivary total antioxidant capacity in smokers. in this single blind crossover clinical trial, the whole unstimulated saliva of 30 smokers, who were randomly divided into two groups, was collected. in the first phase after the saliva collection, one group of patients took 500 mg of vitamin c powder, for 3 weeks. then, saliva of...

Cadexomer iodine (Iodosorb) is a hydrophilic starch powder containing iodine, which is a suitable dressing for granulating wounds such as venous ulcers. A total of 61 outpatients with chronic venous ulcers participated in a randomised optional crossover trial using cadexomer iodine or a standard dressing for their ulcers. The trial lasted for 24 weeks or until the ulcer had healed. Two patients...

background: hydroxymethylglutaryl‑coenzyme a reductase inhibitors (statins) are antihyperlipidemic drugs with an established efficacy in stabilizing atherosclerotic plaques and preventing atherogenesis and reducing cardiovascular events. the purpose of this study was to determine the effect of simvastatin on serum vitamin d status in dyslipidemic patients as vitamin d status has an impact on mo...

Proportional Integral Derivative (PID) controllers are used in general to control a system, for example DC motor system. The difficulty of using the controller is parameter tuning, because tuning parameters still use trial and error method find PID constants, namely Gain (KP), (KI) (KD). In this case, genetic algorithm which can give better results each iteration. Genetic algorithms one smart m...

Epidural motor cortex stimulation (MCS) has been proposed as a treatment for chronic, drug-resistant neuropathic pain of various origins. Regarding pain syndromes due to peripheral nerve lesion, only case series have previously been reported. We present the results of the first randomized controlled trial using chronic MCS in this indication. Sixteen patients were included with pain origin as f...

This paper presents a weight optimization method for nonlinear model predictive controller (NMPC) based on the genetic algorithm (GA) ship trajectory tracking. The coefficients Q and R of objective function in NMPC are obtained via real-time instead trial error method, which improves efficiency accuracy controller. In addition, targeted improvements made to internal crossover operator, mutation...

BACKGROUND Intake of free sugars in the population exceeds recommendations, with the largest source in the diet being sugar-sweetened beverages (SSBs). SSB consumption is linked to adverse health consequences and contributes to health inequalities, given greater consumption amongst the most deprived. One possible intervention is to reduce the available sizes of SSB packaging but there is an abs...

BACKGROUND Complex Regional Pain Syndrome (CRPS) is a disabling disease that is sometimes difficult to treat. Although spinal cord stimulation (SCS) can reduce pain in most patients with CRPS, some do not achieve the desired reduction in pain. Moreover, the pain reduction can diminish over time even after an initially successful period of SCS. Pain reduction can be regained by increasing the SC...