The object of this paper is to present a modified view of the mode of action of phrenic nerve crush and pneumoperitoneum therapy in pulmonary tuberculosis. In a study of mediastinal shift in a series of 80 cases of phrenic nerve crush and pneumoperitoneum therapy (Fox, 1950) it was found that the average mediastinal shift to the left in the cases with right phrenic paralysis was 1.6 cm., and to...

BACKGROUND AND PURPOSE Few reports exist concerning the peak serum concentration of creatine kinase (CK) and the severity of crush syndrome, and the efficacy of fasciotomy in crush syndrome patients remains controversial. This study aimed to analyze and assess the clinical features, treatment, and outcome of patients with crush syndrome sustained in the Chi-Chi earthquake in September 21, 1999....

PURPOSE The sigma-1 receptor (σR1), a ligand-operated chaperone, has been inferred to be neuroprotective in previous studies using σR1 ligands. The σR1 specificity of the protective function, however, has yet to be firmly established, due to the existence of non-σR1 targets of the ligands. Here, we used the σR1-knockout mouse (Sigmar1(-/-)) to demonstrate unambiguously the role of the σR1 in pr...

Peripheral nerve injuries induce long-lasting physiological and severe functional impairment due to motor, sensory, autonomic denervation. Preclinical models allow us study the process of damage, evaluate capacity peripheral nervous system for spontaneous recovery, test diagnostic tools assess damage subsequent recovery. Methods: In this on Sprague-Dawley rats, we: 1) compared use two different...

PURPOSE To determine whether optical coherence tomography (OCT) is useful for quantitative evaluation of the thickness of the rat retinal nerve fiber layer (RNFL) in an optic nerve crush model. METHODS An OCT system was developed with a modified commercial time-domain OCT and a superluminescent diode with a bandwidth of 150 nm. Optical components were optimized to acquire rat retinal images. ...