BACKGROUND TT virus (TTV) is a recently discovered human DNA virus with worldwide distribution, but with no clear disease association. The possibility of an enhanced TTV virulence in patients with immunodeficiencies has not yet been investigated but is of particular interest because other viruses have been demonstrated to cause severe and rapid liver disease in such patients. Here we analysed t...

Background and Aim: For intermediate HCC (hepatocellular carcinoma) with preserved liver function, Transarterial chemoembolization (TACE) is a standard therapy. Underlying disease reduces the net functionality of liver, hence post-TACE hepatic decompensation an important complication.Various pretreatment predictors have been studied to predict outcomes in HCC.Child-Pugh score ALBI are used asse...

five years survival for decompensated cryptogenic cirrhosis has been reported less than 14%. the patient is a 70 years old man who had cryptogenic cirrhosis since the last 22 years after splenectomy. he had episodes of upper gi bleeding and ascitis at least for the last 17 years. he is still alive and is doing his daily work appropriately.

background: gastrointestinal and liver diseases (gild) constitute a noteworthy portion of causes of death and disability in iran. however, data on their prevalence and burden is sparse in iran. the global burden of disease (gbd) study in 2010 has provided invaluable comprehensive data on the burden of gild in iran methods: estimations of death, years of life lost due to premature death (yll), y...

materials and methods in this case-control study, using the polymerase chain reaction (pcr), adrs266729 and rs2241766 gene polymorphisms were genotyped in b-type ultrasonography-proven nafld patients, with (n = 246) or without (n = 247) cad and in healthy controls (n = 304). serum lipid profiles were determined using biochemical methods. statistical analyses were performed using spss 17.0 stati...

BACKGROUND End-stage liver diseases are common in Iran. The only therapeutic option for these patients is liver transplantation. OBJECTIVE To present our 2-year experience of liver transplantations in Afzalipoor Hospital, Kerman, southeastern Iran. METHODS From November 2009 to September 2011, 12 patients underwent orthotopic liver transplantation in our center. Their data including demogra...

conclusions pain management in patients with liver dysfunction is always challenging to physicians because of the adverse reactions of drugs, especially opioids. opioids should be used cautiously since they can cause sedation, constipation and sudden encephalopathy effects. since the clearance of these drugs in patients with hepatic insufficiency is decreased, the initial dose must be decreased...

introduction: chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. the pediatric end-stage liver disease (peld) score and model of end-stage liver disease (meld) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. the aim of this study is evaluation of relation be...

BACKGROUND AND PURPOSE The cause of initial ischemic stroke in up to 30% of young patients remains unclear. Fabry disease, due to deficient alpha-galactosidase A (alpha-Gal A) activity, is a vascular endothelial glycosphingolipid storage disease typically presenting in childhood. With advancing age, patients develop renal, cardiac, and cerebrovascular disease and die prematurely. A European stu...

Abstract Background Congenital hepatic fibrosis (CHF) is a rare disorder of the porto-biliary system occurring due to defective remodeling ductal architecture leading progressive portal tract. Though classically, CHF has been reported be associated with autosomal recessive polycystic kidney disease (ARPKD), there have only few reports associating dominant (ADPKD). Also, lack proper sequencing p...