UNLABELLED The aim of this study was to investigate the diagnostic accuracy and impact on patient management of the new integrated PET/CT modality in patients with suspected iodine-negative, differentiated thyroid carcinoma (DTC). METHODS Forty patients with DTC and a suggestion of iodine-negative tumor tissue underwent PET/CT examination (370 MBq (18)F-FDG, coregistered PET/CT whole-body ima...

  The advent of dual-modality PET/CT imaging has revolutionized the practice of clinical oncology, cardiology and neurology by improving lesions localization and the possibility of accurate quantitative analysis. In addition, the use of CT images for CT-based attenuation correction (CTAC) allows to decrease the overall scanning time and to create a noise-free attenuat...

UNLABELLED The purpose of this study was to investigate the clinical usefulness of PET/CT or CT-attenuated PET in the evaluation of patients with oral cavity cancer (OCC) in whom dental artifacts distorted the conventional CT or MR images of the oral cavity. METHODS A PET/CT scan, in addition to a CT or MRI scan, was performed in 69 patients with OCC who had dentures or dental implants. A tot...

The modern practice of radiation therapy relies on volumetric patient images. Computed tomography (CT) imaging has been the primary imaging modality used in radiation oncology for over two decades. However, magnetic resonance imaging (MRI) and positron emission tomography (PET) are increasingly becoming an important component of the treatment planning process. CT studies provide information not...

UNLABELLED Cardiac PET combined with CT is rapidly expanding despite artifactual defects and false-positive results due to misregistration of PET and CT attenuation correction data-the frequency, cause, and correction of which remain undetermined. METHODS Two hundred fifty-nine consecutive patients underwent diagnostic rest-dipyridamole myocardial perfusion PET/CT using (82)Rb, a 16-slice PET...

Medical image registration plays an important role in clinical diagnosis and therapy planning. This paper proposes an automatic method to register computed tomography (CT) and magnetic resonance (MR) brain images by using first principal directions of feature images. In this method, principal component analysis (PCA) neural network is used to calculate the first principal directions from featur...

OBJECTIVE To determine the role of computed tomography-virtual cystoscopy (CT-VC) in the detection and evaluation of bladder cancer, compared to standard conventional cystoscopy (CC). PATIENTS AND METHODS Twenty-five patients with a clinical presentation of a bladder mass(es) were selected from an outpatient urology clinic between May 2011 and August 2012. All patients were then assessed usin...

PURPOSE Whole-body positron emission tomography/computed tomography (PET/CT) has become a standard method of imaging patients with various disease conditions, especially cancer. Body-wide accurate quantification of disease burden in PET/CT images is important for characterizing lesions, staging disease, prognosticating patient outcome, planning treatment, and evaluating disease response to ther...

OBJECTIVE To evaluate the reliability of virtual non-contrast (VNC) images reconstructed from contrast-enhanced, dual-energy scans compared with true non-contrast (TNC) images in the assessment of high CT attenuation or calcification of mediastinal lymph nodes. MATERIALS AND METHODS A total of 112 mediastinal nodes from 45 patients who underwent non-contrast and dual-energy contrast-enhanced ...

CT is the preferred imaging modality to diagnose pulmonary embolism Evaluation of pulmonary embolism with dual energy CT (DECT) retains diagnostic accuracy using less contrast material than standard CT Virtual monochromatic images, derived from DECT data, show contrast material at greater intensity than standard CT Iodine images show the distribution of contrast material and can be used to asse...