A Nafion-modified glassy carbon electrode incorporated with tobramycin for the voltammetric stripping determination of Cu2+ has been explored. The electrode was fabricated by tobramycin containing Nafion on the glassy carbon electrode surface. The modified electrode exhibited a significantly increased sensitivity and selectivity for Cu2+ compared with a bare glassy carbon electrode and the Nafi...

A recombinant trypsin was designed whose catalytic activity can be regulated by varying the concentration of Cu2+ in solution. Substitution of Arg-96 with a His in rat trypsin (trypsin R96H) places a new imidazole group on the surface of the enzyme near the essential active-site His-57. The unique spatial orientation of these His side chains results in the formation of a stable, metal-binding s...

The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been implicated in mediating the response to vascular injury. Because the Cu2+-binding proteins IL-1alpha and fibroblast growth factor 1 are exported into the extracellular compartment in a stress-dependent manner by using intracellular Cu2+ to ...

The ground-state spin arrangement and the bipartite entanglement within Cu2+-Cu2+ dimers across magnetization process of 4f-3d heterometallic coordination polymer [Dy(hfac)2(CH3OH)2Cu(dmg)(Hdmg)2]n (H2dmg = dimethylglyoxime, Hhfac 1,1,1,5,5,5-hexafluoropentane-2,4-dione) are theoretically examined using symmetric isotropic spin-1/2 Ising–Heisenberg orthogonal-dimer chain. numerical results poin...

Superoxide (O2-.) was reduced by the addition of superoxide dismutase (SOD: O2-. scavenger) and catechins. In competitive reactions utilizing different concentrations of spin-trap agent, the IC50 values of each sample were changed. With regard to the Cu2+/H2O2 and Fe2+/H2O2 reaction systems, metal chelater, hydroxyl radical (.OH) scavenger and catechins eliminated the levels of .OH. For the Cu2...

Froth flotation has been a key chemical process extensively used in the recovery of heavy metal ions (e.g. Cu2+) from contaminated water, while often criticized by secondary pollution added collectors, and less selectivity to specific since ion removal particles is independent post-step particle flotation. To facilitate industrial operation, “smart” with foams responsively stabilized after sele...

Abstract: In this study, a novel method based on a Bi/glassy carbon electrode (Bi/GCE) for quantitatively and directly detecting Cd2+ in the presence of Cu2+ without further electrode modifications by combining square-wave anodic stripping voltammetry (SWASV) and a back-propagation artificial neural network (BP-ANN) has been proposed. The influence of the Cu2+ concentration on the stripping res...

Ceruloplasmin and transferrin are proteins which play a potential role in the process of breast cancer development. These molecules contain Cu2+ (ceruloplasmin) or Fe3+ ions (transferrin) and thus constitute paramagnetic centers, which can be studied using electron paramagnetic resonance method. The aim of the study was to determine how paramagnetic centers in whole blood of breast cancer patie...

SPARC is a transiently expressed extracellular matrix-binding protein that alters cell shape and regulates endothelial cell proliferation in vitro. In this study, we show that SPARC mRNA and protein are synthesized by endothelial cells during angiogenesis in vivo. SPARC and peptides derived from a cationic region of the protein (amino acids 113-130) stimulated the formation of endothelial cords...

The syntheses and single crystal X-ray analyses of five strapped salicylaldoxime/salicylaldimine based dicopper(ii) receptors utilising a new piperazine linker are described. The complexes form 2 + 2 metallocycles and the molecular structures of all four complexes possess a small internal cavity with the utilisation of a short piperazine linker. The molecular structures of complexes [Cu2(L(4) -...