Albizia gum has been evaluated as a binding agent in tablet formulations in comparison with gelatin BP. Compressional properties were analyzed using density measurements and the compression equations of Heckel and Kawakita as assessment parameters, while the mechanical properties of the tablets were assessed using the crushing strength and friability of the tablets. Drug release properties of t...

We constructed deletion mutants and seven point mutants by polymerase chain reaction to investigate the specificity of feline foamy virus integrase functional domains. Complementation reactions were performed for three enzymatic activities such as 3'-end processing, strand transfer, and disintegration. The complementation reactions with deletion mutants showed several activities for 3'-end proc...

In 1950 Maharam asked whether every disintegration of a σ-finite measure into σ-finite measures is necessarily uniformly σ-finite. Over the years under special conditions on the disintegration, the answer was shown to be yes. We show here that the question is equivalent to the existence of a Borel uniformization of a certain set defined from the disintegration. Moreover, we show that the answer...

The cyanobacterium semi-filamentous multicellular strain ABRG5-3 undergoes cell lysis as a unique feature that occurs due to growth condition changes from normal cultivation with shaking to static cultivation without shaking in liquid culture (Nishizawa et al., 2010). Microscopic observation and energy dispersive X-ray spectrometer (EDX) analysis have revealed that lysis is involved in the accu...

Microinjection of muscle 6-phosphofructokinase (PFK; EC 2.7.1.11) into tissue culture cells led to a reversible disintegration of microfilament bundles (stress fibers). The mode of disruption as well as of recovery of stress fibers was very similar to that found previously in experiments performed with the actin-severing protein brevin, an extracellular variant of gelsolin. PFK, like brevin, wa...

This work aims at optimizing sludge pretreatment by non-isothermal sonication, varying frequency, US power (PUS) and intensity (IUS varied through probe size), as well as hydrostatic pressure and operation mode (continuous vs. sequential - or pulsed - process). Under non isothermal sonication sludge solubilization results from both ultrasound disintegration and thermal hydrolysis which are conv...

Motivated by the disintegration of supply networks observed in the automotive, textile and electronics industry, we discuss the impact of such phenomena on the network players. We hypothesize that the state of disintegration is not sustainable and will be followed by an eventual reintegration. We present evidence from a field study that was conducted to understand the impact of disintegration o...

Pediatric, ibuprofen containing orodispersible tablets (ODTs) were prepared using the SeDeM expert system methodology. In order to facilitate formulation, directly compressible ibuprofen was employed (Ibuprofen DC 8TM) and characterized using its SeDeM profile. The mannitol based superdisintegrant Ludiflash® was characterized by the SeDeM-ODT expert system, which also allowed calculation of the...

Tablets with 250 mg of Rhodiola rosea L. extract disintegrating in less than 10 min were developed. The influence of the extract content and type of fillers and disintegrants on disintegration time and tablet hardness was evaluated. Type of the filler and the extract/filler ratio but not the type of disintegrant determined fast disintegration of the tablets. It was demonstrated that the extract...