The energy deficiency and environmental problems have motivated researchers to develop conversion systems into a sustainable pathway, the development of catalysts holds center research endeavors. Natural such as metalloenzymes maintained cycles on Earth, thus proving themselves optimal catalysts. In previous results, structural functional analogs enzymes nano-sized electrocatalysts shown promis...

A group of active-site metal coordinating inhibitors of zinc proteases (carboxypeptidase A, thermolysin, Bacillus cereus neutral protease, and angiotensin-converting enzyme) have been synthesized and their properties investigated. Their general structures are R-SH and R-NH-PO2(O phi)H, where-S- or -O- serve as metal ligands and R refers to an amino acid or peptide group designed to interact wit...

Artificial metalloenzymes (ArMs) are created by embedding a synthetic metal catalyst into protein scaffold. ArMs have the potential to merge catalytic advantages of natural enzymes with reaction scope catalysts. The choice scaffold is utmost importance tune activity ArM. Herein, we show repurposing HaloTag, self-labeling widely used in chemical biology, create an ArM for metathesis. This monome...