نتایج جستجو برای: curriculum renewal
تعداد نتایج: 62459 فیلتر نتایج به سال:
Spermatogonial stem cells (SSCs) represent a unique population of germ cells with self-renewal potential. Although reactive oxygen species (ROS) are considered toxic to germ cells, we recently showed that moderate levels of ROS are required for SSC self-renewal and that Nox1 is involved in ROS generation. In this study, we showed that self-renewal factor treatment induces Nox3 to trigger SSC se...
BMP signaling is essential for promoting self-renewal of mouse embryonic stem cells and Drosophila germline stem cells and for repressing stem cell proliferation in the mouse intestine and skin. However, it remains unknown whether BMP signaling can promote self-renewal of adult somatic stem cells. In this study, we show that BMP signaling is necessary and sufficient for promoting self-renewal a...
Stem cells (SC) exhibit a unique capacity for self-renewal in an undifferentiated state. It is unclear whether the self-renewal of pluripotent embryonic SC (ESC) and of tissue-specific adult SC such as hematopoietic SC (HSC) is controlled by common mechanisms. The deletion of transcription factor Zfx impaired the self-renewal but not the differentiation capacity of murine ESC; conversely, Zfx o...
Background Urban renewal has become an important issue in Hong Kong, which is experiencing considerable population growth pressures and urban decay in various districts. Ho et al. [1] noted that urban renewal often creates not only environmental problems such as demolition waste, but also social problems such as destruction of existing social networks and the fabric of long-established communit...
The construction business network is generally seen as conservative and non-innovative, for which a number of reasons have been identified. One of which relates to the special interorganisational setting that exists within the industry. The starting point of our study was to investigate whether there is any truth in this perceived lack of innovation. One reason for the industry’s bad reputation...
introduction: an evaluation of the curriculum elements can be recognized as a necessity in curriculum dynamic and improvement. this study aimed at evaluating five main elements of a physiopathology curriculum in internal medicine (objectives, content, methods, evaluation, and management). method: the present study is of a descriptive-analytical type, and the study population consisted of a tota...
Hematopoietic stem cells (HSCs) are generally defined by their dual properties of pluripotency and extensive self-renewal capacity. However, a lack of experimental clarity as to what constitutes extensive self-renewal capacity coupled with an absence of methods to prospectively isolate long-term repopulating cells with defined self-renewal activities has made it difficult to identify the essent...
Despite the fact that porcine embryonic stem cells (ESCs) are a practical study tool, in vitro long-term maintenance of these cells is difficult in a two-dimensional (2D) microenvironment using cellular niche or extracellular matrix proteins. However, a three-dimensional (3D) microenvironment, similar to that enclosing the inner cell mass of the blastocyst, may improve in vitro maintenance of s...
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