PURPOSE An increase in corneal temperature has been implicated in subepithelial haze after surface photorefractive keratectomy. We aimed to determine if cooling the cornea by means of hydration between ablations and immediately after final surface ablation in PRK reduces haze. METHODS One hundred five eyes of 61 patients with myopia ranging from -6.00 to -9.75 D were included. One of the surg...

INTRODUCTION Chilled saline is commonly used to irrigate the ocular surface after photorefractive keratectomy (PRK) and is often considered by the patients to be uncomfortable. Room temperature (non-chilled) saline may be a safe and less painful alternative. OBJECTIVES To compare pain and visual outcomes after irrigating the ocular surface with chilled saline versus room temperature saline in...

Purpose: To compare changes in posterior corneal elevation, anterior chamber depth (ACD), anterior chamber volume (ACV) and corneal volume (CV) after laser in situ keratomileusis (LASIK ) and photorefractive keratectomy (PRK) for low to moderate myopia by pentacam imaging Methods: In this prospective comparative case series, 105 consecutive myopic eyes randomly scheduled for LASIK (n=59) or PRK...

PURPOSE To evaluate the optical quality after laser in situ keratomileusis (LASIK) or serial photorefractive keratectomy (PRK) using a double-pass system and to follow the recovery of optical quality after laser vision correction. METHODS This study measured the visual acuity, manifest refraction and optical quality before and one day, one week, one month, and three months after laser vision ...

PURPOSE The corneal change induced by refractive procedures influence both the postoperative refractive status and the ocular spherical aberration (SA). We evaluated changes in corneal SA after three types of surface ablation: phototherapeutic keratectomy (PTK), myopic photorefractive keratectomy (PRK), and myopic wavefront-guided laser epithelial keratomileusis (LASEK). METHODS Twenty-six ey...

PURPOSE To describe the incidence and risk factors associated with microbial keratitis in a large population of laser vision correction (LVC) patients. SETTING Optical Express centers, Glasgow, United Kingdom. DESIGN Retrospective case series. METHODS Records were searched to identify all cases of presumed microbial keratitis after LVC between January 1, 2008, and April 1, 2015. Consecuti...

Many key cellular functions, such as cell motility and cellular differentiation are mediated by Rho-associated protein kinases (ROCKs). Numerous studies have been conducted to examine the ROCK signal transduction pathways involved in these motile and contractile events with the aid of pharmacological inhibitors such as Y-27632. However the molecular mechanism of action of Y-27632 has not been f...

AIM To evaluate the effect of topical vitamin A supplementation on corneal re-epithelialization time, postoperative pain, visual acuity, and haze following photorefractive keratectomy (PRK). PATIENTS AND METHODS This prospective study included 32 patients. For each patient, one eye was randomized to the vitamin A group and the fellow eye to the non-vitamin A group (control group). Eyes in the...

The chloroplast enzyme phosphoribulokinase (PRK; EC 2.7.1.19) is part of the Calvin cycle (reductive pentose phosphate pathway) responsible for CO(2) fixation in photosynthetic organisms. In green algae and vascular plants, this enzyme is light regulated via reversible reduction by reduced thioredoxin. We have sequenced and characterized the gene of the PRK from the marine diatom Odontella sine...

PURPOSE To evaluate possible changes of the ocular rigidity coefficient in vivo after photorefractive keratectomy (PRK) in a series of rabbit eyes, using an invasive ocular rigidity measurement device. METHODS Sixteen eyes of 8 rabbits were used in this study. One eye from each rabbit underwent PRK for -10.00 diopters (D) in a 5-mm optical zone (92 microm) while the fellow eye served as the c...