One of the most consumed caffeinated soft drinks by millions people globally is Coca-Cola. For healthy adults, caffeine consumption relatively safe, but for some vulnerable populations, could be harmful. Therefore, we considered this cytogenetic study to appropriate assessment cytotoxicity effects Coca-Cola in meristematic cells plants, through Allium test. A. cepa has assayed one best model pl...

This in vitro study evaluated the detrimental effect of acute gamma (γ)-irradiation on rat immature hippocampal neurons. Rat immature hippocampal neurons (0.5 day in vitro) were irradiated with 0~4 Gy γ-rays. Cytotoxicity was analyzed using a lactate dehydrogenase release assay at 24 h after γ-irradiation. Radiation-induced cytotoxicity in immature hippocampal neurons increased in a dose-depend...

Chemical investigation into the ethyl acetate extract of endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The were characterized by spectroscopic methods including NMR (1D 2D) HRMS. cytotoxicity crude isolated against normal human lung fibroblast cells, lineage GM07492A, was evaluated XTT assay. To best our knowledge, this is first ch...

Introduction : The triphenyl phosphonium residue is a well-documented mitochondriotropic that has been shown to improve the accumulation of biomolecules in mitochondria. Stearyl (STPP) modified liposomes have facilitate selective various mitochondria resulting improved effect in-vitro and in-vivo. More recently, STPP was reported higher toxicity towards drug resistant ovarian cancer cell line c...

BACKGROUND Novel approaches to treat human cancer that are effective with minimal toxicity profiles are needed. We evaluated gold nanoparticles (GNPs) in human hepatocellular and pancreatic cancer cells to determine: 1) absence of intrinsic cytotoxicity of the GNPs and 2) external radiofrequency (RF) field-induced heating of intracellular GNPs to produce thermal destruction of malignant cells. ...

The biocompatibility and biodegradability of magnesium (Mg), along with its lightness, make magnesium-based materials promising for use in the biomedical industry. In this work, ternary Mg–Zn–Ca alloys were manufactured applications using mechanical alloying (MA). objective work was to study effect milling time on produced Mg65–Zn30–Ca5 Mg70–Zn25–Ca5 (percentages by weight), degradation synthet...

The optimization of biomaterials’ biodegradation rate similar to tissue regeneration, is one of the main goals of tissue engineering. However, the necessity to assess their possible toxicity is always considered. The aim of this study was cytotoxicity and genotoxicity evaluation of fluorapatite/bioactive glass (FA/BG) nanocomposite foams with two various weight ratios to determine the optimal c...