With the growing use of quantum-dot cellular automata (QCA) nanotechnology, digital circuits designed at Nanoscale have a number advantages over CMOS devices, including lower utilization power, increased processing speed circuit, and higher density. There are several flip flop designs proposed in literature with their realization QCA technology. However, majority these suffer from large cell co...

The logic construction of a double-edge-triggered (DET) flip-flop, which can receive input signal at two levels of the clock, is analyzed and a new circuit design of CMOS DET flip-flop is proposed. Simulation using SPICE and a 1μ technology shows that this DET flip-flop has ideal logic functionality, a simpler structure, lower delay time, and higher maximum data rate compared to other existing ...

We show how to simulate a roll of a fair n-sided die by one flip of a biased coin with probability 1/n of coming up heads, followed by 3⌊log 2 n⌋+ 1 flips of a fair coin. Let a p-coin be a biased coin with probability p of coming up heads. A fair coin is a (1/2)-coin. A fair n-sided die is a die with n sides, each of which comes up with probability 1/n when the die is rolled. Proposition 1. For...

Understanding the mechanism of cisplatin (CDDP) action may improve therapeutic strategy for ovarian cancer. Although p53 and FLICE-like inhibitory protein (FLIP) are determinants of CDDP sensitivity in ovarian cancer, the interaction between p53 and FLIP remains poorly understood. Here, using two chemosensitive ovarian cancer cell lines and various molecular and cellular approaches, we show tha...

This paper explores the energy-delay space of eight widely referred flip-flops in a 0.13μm CMOS technology. The main goal has been to find the smallest set of flip-flop topologies to be included in a “high performance” flip-flop cell library covering a wide range of power-performance targets. Based on our comparison results, transmission gate-based flipflops show the best power-performance trad...