نتایج جستجو برای: daa
تعداد نتایج: 1085 فیلتر نتایج به سال:
BACKGROUND Hepatitis C is a blood-borne virus primarily spread through sharing of drug-injecting equipment. Approximately 150 million people worldwide and 230,000 Australians are living with chronic hepatitis C infection. In March 2016, the Australian government began subsidizing direct acting antivirals (DAAs) for the treatment of hepatitis C, which are highly effective (95% cure rate) and hav...
Synthesis and molecular docking of pyrazole derivatives using the heterogeneous basic, CS-DAA/MgO nanocomposite.
Multipactor suppression in dielectric-assist accelerating structures via diamondlike carbon coatings
Multipactor discharges are widely observed in the accelerator field, and their suppression has been studied to improve performance. A dielectric-assist accelerating (DAA) cavity is a standing-wave that attains Q-value of over 100,000 at room temperature by using reflection dielectric layer; DAA expected be used with small RF power source high-duty operation. Thus far, maximum field cavities lim...
Background: Hepatocellular carcinoma makes up 75%-85% of all primary liver cancers and is the fourth most common cause cancer related death worldwide. The aim this study was to screen for hepatocellular in hepatic patients who received direct acting antiviral drugs using different imaging modalities. Methods: This a cross sectional included 50 were Direct Acting Antiviral '' DAA'' carried out a...
BACKGROUND Intracellular HCV-RNA reduction is a proposed mechanism of action of direct-acting antivirals (DAAs), alternative to hepatocytes elimination by pegylated-interferon plus ribavirin (PR). We modeled ALT and HCV-RNA kinetics in cirrhotic patients treated with currently-used all-DAA combinations to evaluate their mode of action and cytotoxicity compared with telaprevir (TVR)+PR. STUDY ...
BACKGROUND AND AIMS Increased levels of chemokine interferon-gamma (IFN-γ)-inducible protein-10 (CXCL10), soluble CD163 (sCD163) and soluble CD14 (sCD14) have been reported in HCV infection. The aim of this study was to compare, sCD163 and sCD14 levels in HCV-infected patients undergoing direct acting antiviral (DAA)-containing regimens with or without interferon (IFN). METHODS sCD163, sCD14 ...
D-aspartic acid (DAA), nitrate, and vitamin D3 have received considerable attention in recent years for their potential health-enhancing properties. Using an open-label design, we evaluated the impact of a DAA/sodium nitrate/ vitamin D3 dietary supplement on blood testosterone and nitrate/nitrite, as well as subjective indicators of health, in middle-aged men. Methods: 10 overweight or obese me...
BACKGROUND AND AIM Hepatitis C viral infection (HCV) has become a curable disease due to the development of direct acting antivirals (DAA). The WHO has set a target to eliminate HCV completely. Therefore, people who inject drugs (PWID) also need to be treated. In this study, we compared the real-life uptake and outcome of DAA treatment for HCV in PWID and non-PWID. METHODS We performed a nati...
We previously reported that an apparent water potential disequilibrium is maintained late in muskmelon (Cucumis melo L.) seed development between the embryo and the surrounding fruit tissue (mesocarp). To further investigate the basis of this phenomenon, the permeability characteristics of the tissues surrounding muskmelon embryos (the mucilaginous endocarp, the testa, a 2- to 4-cell-layered pe...
Background and Aims: The lack of specificity has limited the role of serum alpha-fetoprotein (AFP) for hepatocellular carcinoma (HCC) screening among patients with cirrhosis related to hepatitis C virus (HCV) infection. We sought to examine whether AFP may decrease after achieving a sustained virological response (SVR) in patients with HCV-related cirrhosis. Methods: We performed a retrospectiv...
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