Criteria for experimental observation of multi-dimensional optical solitons in media with saturable refractive nonlinearities are developed. The criteria are applied to actual material parameters (characterizing the cubic self-focusing and quintic self-defocusing nonlinearities, two-photon loss, and optical-damage threshold) for various glasses. This way, we identify operation windows for solit...

PURPOSE To evaluate the validity of different methods of relative afferent pupillary defect (RAPD) detection and assess the usefulness of detecting an RAPD in glaucoma patients. METHODS For this prospective observational study, we enrolled 70 of 153 consecutive glaucoma patients coming for examination. Exclusion criteria were cloudy corneas, recent surgery, fixed pupils, and other diseases pr...

OBJECTIVES Juvenile idiopathic arthritis (JIA) is subdivided into seven categories. Even within these categories, the prognosis varies markedly. To start appropriate treatment in patients with JIA and to inform patients and their parents correctly, it is essential to know the individual prognosis, preferably at the time of diagnosis. The aim of this study was to identify variables that predict ...

INTRODUCTION Diffuse alveolar damage (DAD) is a morphological prototype of acute interstitial pneumonia. Hospital autopsies or open-lung biopsies are used to monitor common alveolar damage and hyaline membrane (HM) development histopathologically. The aim of this study was to detect histopathological profiles and frequency of DAD and HM in adult forensic autopsies. MATERIALS AND METHODS In to...

Childhood systemic vasculitides are a group of rare diseases with multi-organ involvement and potentially devastating consequences. After establishment of new classification criteria (Ankara consensus conference in 2008), it is now time to establish measures for proper definition of activity and damage in childhood primary vasculitis. By comparison to adult vasculitis, there is no consensus for...

There are three categories of blood eosinophilia: reactive (non-clonal), clonal and Idiopathic hypereosinophilic syndrome (HES). The empirical diagnostic criteria of HES are: blood eosinophilia exceeding 1.5xl09/l for more than six consecutive months; absence of an underlying cause of hypereosinophilia despite extensive diagnostic evaluation and organ damage or dysfunction as a result of local ...

Emergency repair has been successfully performed in acute type A aortic dissection complicated by cerebral malperfusion. Despite the lack of criteria to define irreversible brain damage, immediate surgery is often denied in case of stroke or coma. We report two patients presenting with coma and altered brainstem reflexes shortly after onset of aortic dissection, in whom aortic repair was succes...

PReS-FINAL-2063: Proposed criteria for activity, damage and impact of juvenile idiopathic arthritis associated uveitis: consensus effort from the multinational interdisciplinary working group for uveitis in childhood (MIWGUC) I Foeldvari, A Heiligenhaus, J Anton, R Ramanan, C Edelsten, T Saurenmann, B Bodaghi, K Kotaniemi, S Nielsen, E Rabinovich, Multinational Interdisciplinary Working Group f...

Systemic sclerosis is a complex disease that involves "autoimmunity," "inflammation," "fibrosis," and "vasculopathy." Microvascular damage and dysfunction particularly represent the earliest morphological and functional markers of systemic sclerosis. These morphological changes and progressions can be detected by nailfold videocapillaroscopy (NVC). In 2013, the American College of Rheumatology ...

OBJECTIVE In geriatric populations, frailty is associated with poor health outcomes, including mortality. Frailty has not been examined in lupus, although components of the phenotype seem relevant. METHODS Women with lupus (n=152) participated in research visits in 2008-2009. Frailty was assessed by Fried's frailty phenotype criteria: low weight/unintentional weight loss, slow gait (4-m walk ...