background: the sry gene (sry) provides instructions for making a transcription factor called the sex-determining region y protein. the sex-determining region y protein causes a fetus to develop as a male. in this study, sry of 15 spices included of human, chimpanzee, dog, pig, rat, cattle, buffalo, goat, sheep, horse, zebra, frog, urial, dolphin and killer whale were used for determine of bioi...

PATRICK K. DEVERS,t·2 Depar/fllm! rf rlsheries lmd Wildl!fe Scienas, Virginia Polyttt:hnic blStitule and Stale Uniwnity. Blacksburg, VA 24061, USA DEAN F. STAUFFER, Dtpartmmt rf Fishtl"ies ami Wildlife Scil!1lc(s, Virginia Polytechnic Institute and State Uni'llenity, BI{lrksburg, VA 24061, USA GARY W. NORMAN, Virginia Departmellt C!f Game and Inland Fisheries. P. O. Box 996. VCTfJ71a, VA 24482,...

To increase Navy Nurse Corps manpower management efficiency, we developed a Markov model of the personnel flow of junior officers (O1-O4). The Nurse Corps manages personnel primarily through the recruitment process, drawing on multiple accession sources. Accession sources were shown to have a statistically significant effect on promotion and retention rates. However, these effects were not foun...

Facile and meaningful integration of data from disparate resources is the 'holy grail' of bioinformatics. Some resources have begun to address this problem by providing their data using Semantic Web standards, specifically the Resource Description Framework (RDF) and the Web Ontology Language (OWL). Unfortunately, adoption of Semantic Web standards has been slow overall, and even in cases where...

Psoriasis is a chronic cutaneous inflammatory disease. The immunopathogenesis is a complex interplay between T cells, dendritic cells and the epidermis in which T cells and dendritic cells maintain skin inflammation. Anti-tumour necrosis factor (anti-TNF)-α agents have been approved for therapeutic use across a range of inflammatory disorders including psoriasis, but the anti-inflammatory mecha...

Acknowledgements: The views expressed in this paper are those of the author and do not purport to reflect the positions of the U.S. Military Academy, the Department of the Army, or the Department of Defense. I am grateful to my advisor, Ben Castleman, for advice and encouragement at every stage of this research. David Lyle, Amalia Miller, Luke Miller, Bruce Sacerdote, Bill Skimmyhorn, Sarah Tur...

In this work we revise the layered software architecture for the Knowledge Grid by explicitly introducing the concept of Resourceome, i.e. an “alive” ontology of resources. This approach is necessary to tackle the challenges posed by the “ome” status, reached by the world of bioinformatics resources. The resulting software architecture, a Resourceomic Grid, integrates components to support issu...

This paper starts with a discussion of the sometimes contradictory and incomplete nature of distributed online bioinformatics resources. From this we suggest there is a need for a method to evaluate the data contained in such resources before they are used. The method we put forward uses a form of non-monotonic reasoning called argumentation. Arguments are created to help the user weigh up the ...

UNLABELLED Currently, Saphenous vein (SV) and internal thoracic artery (ITA) are still the most common graft materials in Coronary Artery Bypass Grafting (CABG) whereas SV graft have a lower long-term patency than ITA. Vascular smooth muscle cells (VSMCs) phenotype conversion, proliferation and migration may play a key role in mechanism of vein graft restenosis. To explore differential gene exp...

The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previous...