Materials and methods A total of 500 infertile male patients attending private infertility clinics of Guwahati, Assam, were selected for the study. Blood and semen samples were collected from the patients. Genomic DNA was isolated from both type of samples and PCR amplification was carried out using specific primer sets. The genes and sequence-tagged site (STS) markers included in the study are...

The azoospermia factor (AZF) regions consist of three genetic domains in the long arm of the human Y chromosome referred to as AZFa, AZFb and AZFc. These are of importance for male fertility since they are home to genes required for spermatogenesis. In this paper a comprehensive analysis of AZF structure and gene content will be undertaken. Particular care will be given to the molecular mechani...

Transcriptional activation in early spermatocytes involves hundreds of genes, many of which are required for meiosis and spermatid differentiation. A number of the meiotic-arrest genes have been identified as general regulators of transcription; however, the gene-specific transcription factors have remained elusive. To identify such factors, we purified the protein that specifically binds to th...

HS 0146+1847, originally identified as a white dwarf candidate in proper motion surveys, was rediscovered as a candidate in the Hamburg Quasar Survey. Spectra obtained for the SPY (ESO Supernova Ia Progenitor) survey show strong Balmer and Ca II lines, suggesting a classification as DAZ white dwarf. Contrary to the objects known so far in this class, HS 0146+1847 has a helium-rich atmosphere at...

Male germ cell development includes mitotic and meiotic cell divisions that are followed by dramatic morphological changes resulting in the production of spermatozoa. Genetic evidence has indicated that the DAZ family genes are critical for successful male germ cell development in diverse animals as well as humans. In the present study, we investigated the cellular functions of Dazl in the mous...

This article discusses the online edition of “Deutsche Allgemeine Zeitung” (DAZ, German General Newspaper), an exceptional media product in Kazakhstan. medium was chosen mainly for its very complex linguistic and cultural configuration. The forms are German, while discourse text traditions suggest a Russian influence due to long hegemony as language culture education Additionally, current socio...

O artigo tem por objetivo examinar os contextos de produção dos termos Alemão como Língua Estrangeira, Segunda Língua, Terceira e Adicional empregados na literatura científica para denotar uma L≠1. Mobiliza-se base teórica desse estudo a abordagem discursiva SKAD (Sociology of Knowledge Approach to Discourse; KELLER 2011a, 2011b), que investiga regimes saber em diferentes áreas explora as condi...