α-Bromoketals and acetals are important synthetic precursors in organic synthesis. In this work, some new α-bromoketals are synthesized by the reaction of aryl methyl ketones with diols in the presence of 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) hydrobromide-perbromide in good isolated yields. The latter compound converts aldehydes to acetals and serves as a new and efficient reagent for t...

Organocatalysis for polymer chemistry has become a subject of significant interest in the last two decades. In this contribution, we have studied evolution microstructure poly(L-lactide) solution toluene at 105 °C presence various organocatalysts. Weak bases such as triethylamine and DMAP (4-dimethylaminopyridine) lead to low extent epimerization chain scission reaction. The DBU (1,8-diazabicyc...

A formal, metal-free, [2 + 2 + 2] cycloaddition strategy is described based on a cascade of two pericyclic processes. The first step involves an intramolecular propargylic ene reaction of a 1,6-diyne to generate a vinylallene, which then reacts in an inter- or intramolecular Diels-Alder reaction with an alkenyl or alkynyl dienophile. Reactions involving unsymmetrical alkenyl and alkynyl dienoph...

We previously reported an efficient peptide synthesis method, AJIPHASE®, that comprises repeated reactions and isolations by precipitation. This method utilizes an anchor molecule with long-chain alkyl groups as a protecting group for the C-terminus. To further improve this method, we developed a one-pot synthesis of a peptide sequence wherein the synthetic intermediates were isolated by solven...

Dieser Beitrag beruht auf dem von der DBU geförderten Vorhaben „Verringerung von Risikopotenzialen aufgrund landwirtschaftlicher Nutzung für den Naturschutz im Peenetal“. Es werden hierbei Umweltrisiken in den Randbereichen zu Naturschutzgebieten analysiert, die aus der landwirtschaftlichen Nutzung angrenzender Flächen entstehen. Potenzielle Risiken bestehen hier insbesondere durch Stoffausträg...

Visible light promoted perfluoroalkylation reactions initiated via halogen bonding interactions between perfluoroalkyl iodides (Rf–I, Rf = CnF2n+1) and Lewis bases have been recognized as a powerful tool in the field of radical synthetic chemistry. In order to provide some insights into nature, strength role activation process interactions, we performed combined UV–Visible/Raman/DFT study on mo...