objective(s): in this study, the effect of electrospun fiber orientation on proliferation and differentiation of mesenchymal stem cells (mscs) was evaluated. materials and methods: aligned and random nanocomposite nanofibrous scaffolds were electrospun from polylactic acid (pla), poly (vinyl alcohol) (pva) and calcium carbonate nanoparticles (ncap). the surface morphology of prepared nanofibrou...

objective: the incidence of heart valve disease is increasing worldwide and the number of heart valve replacements is expected to increase in the future. by mimicking the main tissue structures and properties of heart valve, tissue engineering offers new options for the replacements. applying an appropriate scaffold in fabricating tissue-engineered heart valves (tehvs) is of importance since it...

OBJECTIVE This trial was performed to examine the effects of ruminally degradable starch (RDS) levels in total mixed ration (TMR) with low corn-based starch on the milk production, whole-tract nutrient digestibility and nitrogen balance in dairy cows. METHODS Eight multiparous Holstein cows (body weight [BW]: 717±63 kg; days in milk [DIM]: 169±29) were assigned to a crossover design with two ...

21 Three levels of metabolizable protein supply (108, 98–95 and 85 g PDIE kg DM) (PDIE: protein digested in the small intestine when rumen-fermentable energy is limiting) in the diet and three levels of difference between rumen-degradable 21 energy and N (PDIE 2 PDIN 5 0, 10 and 20 g kg DM) (PDIN: protein digested in the small intestine when rumenfermentable nitrogen is limiting) were used in t...

A pivotal issue in research on writing concerns whether the knowledge of how genres are constructed and learned in one discipline/genre can be transferred to other contexts, genres, and disciplines. Yet, studies conducted so far have not presented a unified and complete view of how various writing instructional techniques can result in transferability. This study examined the effect of structur...

In bone tissue reconstruction, the use of engineered constructs created by mesenchymal stem cells (MSCs) that differentiate and proliferate into 3D porous scaffolds is an appealing alternative to clinical therapies. Human placenta represents a possible source of MSCs, as it is readily available without invasive procedures and because of the phenotypic plasticity of many of the cell types isolat...

Although studies in vivo revealed promising results in bone regeneration after implantation of scaffolds together with osteogenic progenitor cells, basic questions remain how material surfaces control the biology of mesenchymal stem cells (MSC). We used human MSC derived from bone marrow and studied the osteogenic differentiation on calcium phosphate surfaces. In osteogenic differentiation medi...

nine multiparous lactating cows averaging 171 days in milk were divided according to days in milk and milk production into three 3×3 latin squares with three 3-week periods to investigate the effect of rumen degradable protein on milk urea nitrogen. diets were formulated to provide 3 concentrations of dietary rumen degradable protein (9.8, 10.8, and 11.8% of dry matter), while rumen undegradabl...