Activation of transcription in eukaryotes requires the concerted action of numerous components of the RNA polymerase II transcriptional apparatus. The degree of dependence on many of these components varies from gene to gene and it is still largely unknown how the requirement for any particular component is determined at any given gene. We show that removal of Gal11 from the yeast transcription...

AIM The purpose of this study was to evaluate the effect of different denture cleansers on the color stability, surface hardness, and roughness of different denture base resins. MATERIALS AND METHODS Three denture base resin materials (conventional heat cure resin, high impact resin, and polyamide denture base resin) were immersed for 180 days in commercially available two denture cleansers (...

HIV cure research holds great potential to eradicate HIV, but the benefit to early trial participants is likely to be small. Moreover, participation carries unknown and possibly significant risks to research participants. This is the risk:benefit ratio challenge of HIV cure research. Although it may be consensual and rational for individuals to participate in HIV cure research that requires a d...

The objective of this review is to discuss emerging concepts in pelvic organ prolapse, in particular, "What is cure?" In a post-trial data analysis of the CARE (Colpopexy and Urinary Reduction Efforts) trial, treatment success varied tremendously depending on the definition used (19.2%-97.2%). Definitions that included the absence of vaginal bulge symptoms had the strongest relationships with t...

In medical history of different nations, there are numerous documents concerning cancer. The present study is an investigation in ancient books to determine the part that medicine of Iran has played in the recognition of cancer. In all 31 Iranian medical and 5 Islamic medicine books mostly from 8 to 18 cent. A.D. have been examined. The findings showed that cancer in ancient medical books of Ir...

fourier transform infrared (ftir) and gel permeation chromatography (gpc) wre respectively utilized in determining the changes in isocyanate (nco) concentration and molecular weight (mw) and its distribution (mwd) in polyurethanes during their cure and postcure stages. samples, originally cured at 45°c, were taken through accelerate aging tests at various temperatures. the ftir and gpc analytic...