نتایج جستجو برای: degree of operating leverage dol
تعداد نتایج: 21175232 فیلتر نتایج به سال:
This paper is an overview of results' on the subword complexity of various classes of languages obtained by iterating a mapping, and more precisely on the asymptotic behaviour of this complexity. In the first section we consider iterated morphisms, that is DOL languages. In this area the subword complexity falls into one of five classes, and class membership can be determined. The second sectio...
Congenital Disorders of Glycosylation (CDG) are human deficiencies in glycoprotein biosynthesis. Previous studies showed that 1 mM mannose corrects defective protein N-glycosylation in cultured fibroblasts from some CDG patients. We hypothesized that these CDG cells have limited GDP-mannose (GDP-Man) and that exogenous mannose increases the GDP-Man levels. Using a well established method to mea...
Hemiasterlin (Hem) and dolastatin (Dol) are marine natural products which are cytotoxic for cancer cells. Hem, a tripeptide, and Dol, a hexapeptide, were conjugated with linkers (L) to the universal BB agonist DPhe-Gln-Trp-Ala-Val-betaAla-His-Phe-Nle-NH2(BA1) and the effects of the Hem-BB and Dol-BB conjugates investigated on NCI-H1299 lung cancer cells. Hem-LA-BA1 and Hem-LB-BA1 inhibited spec...
— Ehrenfeucht conjectured that each language L over a finite alphabet E possesses a test set, that is a finite subset F of L such that every two morphisms on E* agreeing on each string in F also agree on each string in L. We introducé the notion of déviation of a string with respect to a language and use it to give a sufficient condition for the existence of such a test set. Moreover, we prove ...
Despite the widespread implementation of digital learning spaces (DLS) generally in Higher Education and for COVID-19 social distancing guidelines, a coherent unified quantification core aspects DLS on student has remained elusive. Therefore, this work extends earlier Harkin Nerantzi (2021), where we employed Lefebvre’s (1991) Trialectic Space to explain physical, mental, DLS. In present paper,...
COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R2) of 0.972 and 0.531 for training and test groups, respectively. The quality of the mod...
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