In order to enhance and target gene delivery we have previously established a novel method, termed magnetofection, which uses magnetic force acting on gene vectors that are associated with magnetic particles. Here we review the benefits, the mechanism and the potential of the method with regard to overcoming physical limitations to gene delivery. Magnetic particle chemistry and physics are disc...

Recent advances in wireless sensor networks have led to many routing methods designed for energy-efficiency in wireless sensor networks. Despite that many routing methods have been proposed in USN, a single routing method cannot be energy-efficient if the environment of the ubiquitous sensor network varies. We present the controlling network access to various hosts and the services they offer, ...

Magnetofection is a nanoparticle-mediated approach for transfection of cells, tissues, and tumors. Specific interest is in using superparamagnetic iron oxide nanoparticles (SPIONs) as delivery system of therapeutic genes. Magnetofection has already been described in some proof-of-principle studies; however, fine tuning of the synthesis of SPIONs is necessary for its broader application. Physico...

Networked video delivering systems have been developing. When videos are delivered from servers to client sites over a network, they are played without skew time at client sites. Moreover, link overflow does not occur, since capability of links are restricted. The systems allocate resources for meeting these requirements. For effective delivery, it is necessary that a policy of scheduling is es...

Intratumoral infusion is the most commonly used method for viral gene delivery in clinical trials for cancer treatment. However, a potential problem in this approach is that viral vectors may disseminate from tumor to normal tissues during and after the infusion. To reduce the dissemination, we developed a novel method based on a biocompatible polymer, poloxamer 407, which could significantly i...

Abstract: In order to solve the vehicle routing problem with pickup and delivery (VRPPD), this paper proposed an improved quantum genetic algorithm based on different constraint conditions. Firstly, a mathematical model was established aiming at minimizing the dispatching time and the total cost. Secondly, the paper proposes the improved quantum genetic algorithm and non dominated sorting strat...

For contents delivery systems such as video-ondemand service, an optimum design is presented to maximize the utility of the system with priority classes. The willingness-to-pay (WTP) is introduced for a measure of utility, and the optimum design is discussed to maximize the utility (revenue). For the system with two priority classes, the optimum condition is given in terms of the traffic load, ...

CONTEXT Despite nearly 4 million deliveries in the United States each year, minimal information exists on unintended health consequences following childbirth, particularly in relation to delivery method. OBJECTIVE To assess the risk for maternal rehospitalization associated with cesarean or assisted vaginal delivery compared with spontaneous vaginal delivery. DESIGN Retrospective cohort stu...

In this paper, we propose a method to realize compound video (multiple videos on a layout) delivery service for mobile terminals. In the proposed method, we introduce proxies which receive multiple videos from corresponding servers and produce a composite video from the received videos in real-time according to the layouts which users specify. However, if users require sets of videos with sligh...

One can find enough evidence in the IS development (ISD) literature supporting the significance of method adaptation for the realization of an effective ISD. Method adaptation involves a decision making process through which the agent(s) modifies the project situation, including the method and the project context, at hand. This paper aims at exploring how a better delivery of guidance and advic...