background: the unplanned departure of endotracheal tube is one of the main complications for endotracheal intubation. in addition to endotracheal extubation, its movement can also lead to damage to the oral cavity. stabilizing endotracheal tube is the most important factor that can prevent unplanned departure of endotracheal tube as well as its movement. the current study was done with the aim...

In internal membrane-containing viruses, a lipid vesicle enclosed by the icosahedral capsid protects the genome. It has been postulated that this internal membrane is the genome delivery device of the virus. Viruses built with this architectural principle infect hosts in all three domains of cellular life. Here, using a combination of electron microscopy techniques, we investigate bacteriophage...

STUDY OBJECTIVES To determine the effect of feeding tube position (gastric vs small bowel) on adequacy of nutrient delivery and feeding complications, including microaspiration, in critically ill children. DESIGN Randomized controlled trial. SETTING Pediatric ICU in a university teaching hospital. PATIENTS Seventy-four critically ill patients < 18 years of age receiving mechanical ventila...

Early studies have shown that only a small fraction of the nominal nebulizer dose (1–12%) is available for delivery to the lungs in intubated children and adults.1-3 Since then, the characterization of forces governing aerosol delivery in ventilated patients has led to improvements in techniques, and the development of newer aerosol generators with the ability to deliver as much drug to ventila...

Increasing evidence demonstrates that maternal folic acid (FA) supplementation during pregnancy reduces the risk of neural tube defects, but whether FA prevents preterm delivery and intrauterine growth restriction (IUGR) remains obscure. Previous studies showed that maternal lipopolysaccharide (LPS) exposure induces preterm delivery, fetal death and IUGR in rodent animals. The aim of this study...

Multi-moded, anti-resonant hollow-core fibre shows great promise for a range of applications from high power laser delivery to novel, non-linear experiments. Anti-resonant fibers typically guide multiple transverse modes due their large core size, albeit with often differential modal loss. Understanding the behaviour higher order in these fibres is crucial importance if we are exploit benefits ...

background: depression is a kind of sorrow that decreases the level of juiciness. most studies have maintained that psy­chological risk factors have the most profound effect on the development of postnatal depression (pnd). we compared the postnatal depression among the women with elective caesarean and vaginal delivery.  methods: this cross- sectional study was carried out on 120 women 1-4 mon...

Hydrogel Based Metronidazole Bioadhesive Tablet (HMBT) was prepared as a novel vaginal delivery system to achieve Controlled release of drug from the tablet for vaginal candidiasis. The highly swollen hydrogel were prepared by dissolving chitosan in acetic acid solution containing drug, followed by neutralisation with sodium hydroxide and characterized by SEM, DSC and FT-IR and evaluated for % ...

Continuous dopaminergic delivery is recognized for the capacity to ameliorate symptoms in Parkinson's disease (PD). In advanced PD the short comings of orally administered Levodopa/Carbidopa include fluctuations resulting in unstable effect and dyskinesia. Levodopa/Carbidopa intestinal gel, LCIG, (Duodopa®, Abbott Laboratories) is delivered continuously through a percutaneous endoscopic gastros...

We aimed to investigate how can target and optimize pulmonary delivery distribution by changing physicochemical characteristics of instilled liquid.Therefore, we created a new liquids group: a. eligible for desired distribution within lung because of assorted physicochemical characteristics b. capable of being augmented with a broad range of chemicals inertly c. no interference on respiratory f...