Background & Objective: FLT3-ITD mutation detection has been an integral part of diagnostic work ups focused on acute myeloid leukemia. However, some studies have indicated that the mutation is unstable during the various stages of the disease. The purpose of this study was to evaluate the stability of this marker in paired diagnosis-relapse samples using Delta-PCR method. Materials & Methods:...

background and aims: hdv is a defective satellite virus and classified in genus deltavirus. its disease is related and limited to hbv-infected patients. acute infection of delta agent occurs in two different patterns simultaneous infection with both hbv & hdv or super infection of chronically hbv infected patients that lead to more sever type of hepatitis. according to genetic diversity of geno...

For a ring endomorphism $alpha$ and an $alpha$-derivation $delta$, we introduce a concept, so called skew $pi$-Armendariz ring, that is a generalization of both $pi$-Armendariz rings, and $(alpha,delta)$-compatible skew Armendariz rings. We first observe the basic properties of skew $pi$-Armendariz rings, and extend the class of skew $pi$-Armendariz rings through various ring extensions. We nex...

This article examines annihilators in the skew polynomial ring $R[x;alpha,delta]$. A ring is strongly right $AB$ if everynon-zero right annihilator is bounded. In this paper, we introduce and investigate a particular class of McCoy rings which satisfy Property ($A$) and the conditions asked by P.P. Nielsen. We assume that $R$ is an ($alpha$,$delta$)-compatible ring, and prove that, if $R$ is ni...

The most prevalent cystic fibrosis transmembrane conductance regulator (CFTR) mutation causing cystic fibrosis, ΔF508, impairs folding of nucleotide binding domain (NBD) 1 and stability of the interface between NBD1 and the membrane-spanning domains. The interfacial stability defect can be partially corrected by the investigational drug VX-809 (3-[6-[[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclo...

In this study, a mixed $delta$-shock model with discrete-time is defined by combining $delta$-shock and extreme shock models. In this model, a system with multiple states fails in two ways: first, when k interarrival times between two consecutive shocks with magnitude larger than the critical threshold $gamma$ are in $[delta_1, delta _2], delta_1 < delta _2$; and second, when the interarrival t...

‎let $mathcal{a}$ be a unital banach algebra‎, ‎$mathcal{m}$ be a left $mathcal{a}$-module‎, ‎and $w$ in $mathcal{z}(mathcal{a})$ be a left separating point of $mathcal{m}$‎. ‎we show that if $mathcal{m}$ is a unital left $mathcal{a}$-module and $delta$ is a linear mapping from $mathcal{a}$ into $mathcal{m}$‎, ‎then the following four conditions are equivalent‎: ‎(i) $delta$ is a jordan left de...

results 12 (14.8%) patients had positive results for both hdv rna and anti-hdv. the mean alt level was higher in hdv positive patients (75.9 u/ml) than hbv-mono-infected individuals; however, the mean hbv viral load was lower in coinfected patients than hbv-mono-infected patients. phylogenetically, genotype i was the only detected genotype, and the most closely related isolates were of turkish,...

Let $G=(V,E)$, $V={1,2,ldots,n}$, $E={e_1,e_2,ldots,e_m}$,be a simple connected graph, with sequence of vertex degrees$Delta =d_1geq d_2geqcdotsgeq d_n=delta >0$ and Laplacian eigenvalues$mu_1geq mu_2geqcdotsgeqmu_{n-1}>mu_n=0$. Denote by $Kf(G)=nsum_{i=1}^{n-1}frac{1}{mu_i}$ and $t=t(G)=frac 1n prod_{i=1}^{n-1} mu_i$ the Kirchhoff index and number of spanning tree...