Vehicle change in velocity, often referred to as delta-V, is a widely used measure of crash severity. The National Highway Traffic Safety Administration (NHTSA) uses the WinSMASH computer code to estimate delta-V in several of its in-depth crash databases. This study examined the accuracy of WinSMASH longitudinal delta-V estimates in 140 rear crashes by comparison with direct measurements of de...

Social scientists often compare subclasses of populations or manipulatons. For example, in comparing task-completion times across two levels of a manipulations, if one group has faster overall mean response, it is natural to ask if the fastest 10% of the first group has a faster mean than the fastest 10% of the second group, and so on. Delta plots, a type of quantilequantile residual plot used ...

Robust GABA-mediated inhibitory postsynaptic currents (IPSCs) in neurons of the thalamic relay (TC) nuclei are important in sustaining oscillatory activity within thalamic and thalamocortical circuits. The biophysical properties and pharmacological sensitivities of these IPSCs both depend on the subunit combination of postsynaptic gamma-aminobutyric acid-A (GABA(A)) receptors. Recombinant GABA(...

An all-digital PWM-based delta-sigma (ΔΣ) ADC is proposed. This system takes advantages of the duration of a pulse, rather than voltage or current, as the analog operand used in its closed-loop operation. Unlike VCO-based ADCs, this ADC as a linear input sampling stage with adequate uncalibrated performance. Furthermore, the architecture allows inherently matched multi-bit quantizer/DAC blocks ...

issue of the stimulation of charge-pump phase-locked loops for built-in self-test applications. It is shown that three nodes of the PLL qualify for test signal injection. The hardware and methodology for each are discussed. In particular, a comprehensive explanation of the use of delta-sigma modulation in the time domain is provided. Furthermore, implementation issues of analog tests with signa...

In this paper, an Adaptive Delta-Sigma based architecture for High Dynamic Range (HDR) Focal Plane Arrays is presented. The noise shaping effect of the Delta-Sigma modulation in the low end, and the distortion noise induced in the high end of Photo-diode current were analyzed in detail. The proposed architecture can extend the DR for about 20N log2 dB at the high end of Photo-diode current with...

Cannabinoid receptors in the brain (CB(1)) take part in modulation of learning, and are particularly important for working and short-term memory. Here, we employed a delayed-matching-to-place (DMTP) task in the open-field water maze and examined the effects of cannabis plant extracts rich in either Delta(9)-tetrahydrocannabinol (Delta(9)-THC), or rich in cannabidiol (CBD), on spatial working an...

The opioid system influences learning and memory processes. However, neural mechanisms underlying the modulation of hippocampal activity by opioid receptors remain largely unknown. Here, we compared how mu and delta receptors operate within the mouse CA1 network, and used knock-in mice expressing functional delta opioid receptors fused to the green fluorescent protein (DOR-eGFP) to determine ho...

Integrating information across sensory domains to construct a unified representation of multi-sensory signals is a fundamental characteristic of perception in ecological contexts. One provocative hypothesis deriving from neurophysiology suggests that there exists early and direct cross-modal phase modulation. We provide evidence, based on magnetoencephalography (MEG) recordings from participant...

Delta(9)-tetrahydrocannabinol binds cannabinoid (CB(1) and CB(2)) receptors, which are activated by endogenous compounds (endocannabinoids) and are involved in a wide range of physiopathological processes (e.g. modulation of neurotransmitter release, regulation of pain perception, and of cardiovascular, gastrointestinal and liver functions). The well-known psychotropic effects of Delta(9)-tetra...