considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. in enzymatic digestion method extracted teeth as denta...

Inflammatory changes in the dental pulp are accompanied by release of a wide variety of chemical mediators. Nitric oxide, an oxidative free radical produced by the enzyme nitric oxide synthase (NOS), has been implicated in multiple inflammatory processes, which makes it a suitable marker for changes which likely occur following tooth pulp insult. Since limited information on nitric oxide in the...

OBJECTIVE To assess if injection of allogeneic dental pulp tissue particles would improve lameness in horses with naturally occurring osteoarthritis (OA) or soft tissue (ST) injury. DESIGN Prospective, randomized, blinded, and controlled clinical trial and client survey assessment. ANIMALS Forty lame client-owned horses. PROCEDURES Sterile dental pulp, recovered from otherwise healthy foa...

The isolation of human genomic DNA is an important step involved in genetic identity analysis. Also getting optimal quantity and quality of DNA is important as this can alter the results. This consideration is especially important in the field of forensic analysis and genetic identity, where DNA is extracted from extremely small amounts of starting material often recovered from suboptimal stora...

Dens invaginatus is a developmental anomaly that results in an invagination of the enamel organ into dental papilla prior to calcification tissues. Apical fenestration defined as defect which apices perforate mucosa and are exposed oral cavity. These anomalies require multidisciplinary management order give better prognosis patient, since it acts retentive area biofilm, affecting deteriorating ...

background: the use of electric current during application of etch-and-rinse adhesive systems has been recently introduced to decrease microleakage. this study investigated the effects of an electric field produced by an experimental device for the application of a two-step etch-and-rinse adhesive on moist dentin surface. methods: sixty freshly extracted human premolars were used for this study...

INTRODUCTION Dental pulp has neural fibers that produce neuropeptides like Substance P (SP) and calcitonin gene-related peptide (CGRP). The inflammation of dental pulp can lead to an increase amount of SP and CGRP release, especially in symptomatic irreversible pulpitis. Therefore, it can be assumed that neuropeptides have some role in the progression of inflammation of the dental pulp. The aim...

Objective: To evaluate dental age assessment reliability through Tooth Coronal Index (TCI) method. Material and Methods: The cone-beam computed tomography (CBCT) scans of 160 individuals aged between 20-70 years were analyzed in the present study. height crown, i.e., coronal height, pulp cavity, cavity mandibular second premolars first molars calculated then TCI was measured. actual a subject c...

Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in the dental pulp. These events can lead to pulp healing if the infection is not too severe following the removal of diseased enamel and dentin tissues and clinical restoration of the tooth. However, chronic inflamm...