Dental decay prevalence in the primary dentition continues to maintain high levels in the infant population, despite the efforts and advances that have been made in the field of oral health prevention programs [1]. This situation increases the possibilities of pulp involvement due to the presence of deep caries, leading pulp to an irreversible state, implying the need to perform a pulp treatmen...

Introduction: The main aim during any dental treatment is to maintain vital pulp as long as possible. Objective: The aim of this study was to assess clinically the use of MTA in direct pulp capping in adult patient. Method: MTA was performed in two visits treatment protocol on direct pulp capping in adult. Results: Clinical and radiological examination conducted after 7 months post treatment of...

To heal or not to heal? Chemokines as determinants of constructive or destructive inflammatory microenvironments Dear Readers, Dental pulp stem cells gained attention as a subpopulation of postnatal stem cells with the ability of multipotential differentiation. Therefore, these cells, specifically SHED (stem cells from human exfoliated deciduous teeth), have been extensively investigated as a p...

endodontic intervention in necrotic immature permanent teeth is usually a clinical challenge. with appropriate case selection, regenerative treatment can be effective, providing a desirable outcome. however, there is still no consensus on the optimal disinfection protocol or the method to achieve predictable clinical outcome. this article presents two cases of regenerative treatment in necrotic...

a case of multiple pulp stones, a supernumerary tooth and a congenitally missed tooth accompanied by several developmental dental anomalies concurrently affect- ing the upper and lower anterior teeth in an iranian healthy girl is reported. devel- opmental tooth abnormalities are usually found in conjunction with certain diseases or conditions. in the present case, although the patient had consa...

Dental caries is the most common chronic childhood disease. Deep caries and dental trauma are the two main etiologic factors responsible for pulp involvement. Better knowledge of the morphology of the root canals of deciduous teeth can improve the outcome of pulp treatment. In this study, 90 deciduous molar teeth (27 first mandibular molars, 27 first maxillary molars, 22 second mandibular molar...

Exogenous ideal delivery system for biologically active molecules is under intensive investigation. In the present study it was aimed to test the availability of different calcium phosphate biomaterials (CPBs), hydroxyapatite (HA), beta tricalcium phosphate (TCP), and a combination of these (TCP+HA) as dental pulp capping systems on healing of dog dental pulp. Experimentally perforated dental p...

Stem cells have been successfully isolated from a variety of human and animal tissues, including dental pulp. This achievement marks progress in regenerative dentistry. This article reviews the latest improvements made in regenerative dental medicine with the involvement of stem cells. Although, various types of multipotent somatic cells can be applied in dentistry, two types of cells have been...

* Assistant Professor, College of Dental Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal ** Bacteriologist, Govt Medical College and Hospital, Patiala, Punjab, India INTRODUCTION Periapical pathosis is considered as an endogenous infection caused by oral microflora. Bacterial infection of dental pulp results in pulpal destruction and subsequently stimulates an inflammatory cel...

ATP-dependent profiles of phosphofructokinase (PFK) activity were determined in both crude and Sephadex G-25-filtered fractions from rabbit dental pulp. ATP had a dual effect on PFK as an activator and an inhibitor, according to its concentration. Gel-filtered PFK showed a similar profile to that of crude PFK, indicating a lack of low-molecular-weight effector(s) for PFK in rabbit dental pulp. ...