Pain is an unpleasant sensation that originates from ongoing or impending tissue damage. Management of different types of pain (acute, postoperative, inflammatory, neuropathic cancer) is challenging and yet the most frequent issue encountered by clinicians. Pharmacological therapy is the first line of approach for the treatment of pain and opioid drugs are prescribed for acute and chronic pain ...

BACKGROUND Opium abuse is one of the widespread social problems, and one of the most worrying aspects of it is the effect of parents' drug abuse on the fetus. OBJECTIVES The present study has investigated the correlation between opium abuse during pregnancy in mothers with congenital heart defects in their children. MATERIALS AND METHODS From early 2009 to late 2011, for two consecutive yea...

Both UNODC and U.S. surveys of opium poppy cultivation indicated a significant increase in cultivation and potential production in 2007, and production and export of synthetic drugs (amphetamine-type stimulants, crystal methamphetamine and Ketamine) from Burma continued unabated. (Note: 2008 UNODC Cultivation Report statistics were not available by our printing deadline.) The significant downwa...

VIRGINIA BERRIDGE and GRIFFITH EDWARDS, Opium and the people: Opiate use in nineteenth-century England, London, Allen Lane; New York, St. Martin's Press, 1981, 8vo, pp. xxx, 369, £20.00. After reading Opium and the people, one is tempted to believe that opium was the religion of the masses. The drug was omnipresent in Victorian society. It was sold, without restriction, not only by chemists, bu...

The opium poppy, Papaver somniferum, is one of mankind's oldest medicinal plants. Opium poppy today is the commercial source of the narcotic analgesics morphine and codeine. Along with these two morphinans, opium poppy produces approximately eighty alkaloids belonging to various tetrahydrobenzylisoquinoline-derived classes. It has been known for over a century that morphinan alkaloids accumulat...

Background: The direct effect of some opioids on immune cells has been demonstrated. The aim of this study was to assess the apoptotic effect of opium on Jurkat T lymphocyte cells. Methods: Different concentrations of opium (2.86 × 10-3 to 2.86 × 10-11 g/ml) were added to 24-well plates containing 5 × 105 Jurkat cells. Apoptotic events were assessed after 6, 24, and 72 hours by flow-cytometric...

introduction: laryngeal cancer is the second most common cancer involving the respiratory tract, second only to lung cancer. previous studies have shown opium dependency to be a possible risk factor for laryngeal cancer. opium consumption is a major problem in some parts of the world. the aim of this study was to investigate the effect of opium consumption on the pattern of involvement in laryn...

Background: Buprenorphine dependence is a new issue and to our knowledge no scientific papers have been published on treatment of buprenorphine dependency. The goal of this research was to characterize intravenous buprenorphine-dependent individuals with respect to socio-demographic and other background features, and to investigate the effect of methadone in the maintenance treatment of intrave...

the effect of opium addiction on the appearance of different types of arrhythmias after acute myocardial infarction (ami) has been assessed in few studies. this study is aimed to determine the effect of opium on post-mi arrhythmia and also to address the differences in the appearance of different types of arrhythmias after ami between opium addicted and non-addicted patients. in this comparativ...

abstract background: acute opium intoxication is one of the most common causes of poisoning in children in iran. although most cases are accidental, traditional misuse of opium for symptomatic therapy of various childhood diseases also contributes to high rate of opium intoxication in iran. cases: here, we report two cases of opium intoxication in infants resulted from transdermal application o...