Adnan Menderes University School of Medicine, Department of Pediatrics, Division of Neonatology, Aydin, Turkey Adnan Menderes University School of Medicine, Department of Pediatrics, Aydin, Turkey Baskent University School of Medicine, Department of Pediatrics, Division of Neonatology, Ankara, Turkey Corresponding author: Abdullah Baris Akcan, Adnan Menderes University School of Medicine, Depar...

The authors describe the use of a ganglionic blocking agent which acts almost entirely as a peripheral vasodilator with minimal side effects in man. This substance acts almost instantaneously when given intravenously, with the depressor effect quantitatively controlled by regulating the infusion rate without tachyphylaxis over several hours. Depressor effect of the drug disappears 2 to 15 minut...

PREVIOUS studies " have shown that a specific depressor response occurs in normotensive and hypertensive rats following deprivation of dietary potassium. Cortisone restores the lowered blood pressures of such potassium-deficient rats to their initial normotensive' 6 or hypertensive levels. Although a similar depressor response occurs in human subjects, when fed a potassium-deficient diet and in...

The effect of captopril on blood pressure and on the depressor responses to intravenously administered bradykinin was examined in anesthetized normotensive rats during inhibition of prostaglandin synthesis. The hypotensive action of captopril persisted after treatment with indomethacin in doses that markedly suppressed urinary excretion of the prostacyclin metabolite 6-keto prostaglandin F1 alp...