If A(t) is a C1,α-curve of unbounded self-adjoint operators with compact resolvents and common domain of definition, then the eigenvalues can be parameterized C1 in t. If A is C∞ then the eigenvalues can be parameterized twice differentiable. Theorem. Let t 7→ A(t) for t ∈ R be a curve of unbounded self-adjoint operators in a Hilbert space with common domain of definition and with compact resol...

COL1A1: collagen 1 a1 DF: dermatofibroma DFSP: dermatofibrosarcoma protuberans FISH: fluorescence in situ hybridization JXG: juvenile xanthogranuloma PDGFB: platelet-derived growth factor-b INTRODUCTION Spindle cell tumors occur in the pediatric population and can prove to be aggressive clinically, as in the case with dermatofibrosarcoma protuberans (DFSP). Soft tissue sarcomas represent less t...

INTRODUCTION Excision of large dermatofibrosarcoma protuberans in the anterior aspect of the trunk often results in large surgical defects that frequently dictate the need for microsurgical reconstruction. However, this option is not always available. PRESENTATION OF CASE The authors describe two patients with very large anterior trunk dermatofibrosarcoma protuberans: one in the epigastric re...

With Grids, we are able to share computing resources and to provide for scientific communities a global transparent access to local facilities. In such an environment the problems of fair resource sharing and best usage arise. In this paper, the analysis of the LPC cluster usage (Laboratoire de Physique Corpusculaire, CNRS-IN2P3, Clermont-Ferrand, France) in the EGEE Grid environment is done, a...

INSERM U766, Facultés de Médecine et de Pharmacie, Clermont-Ferrand, France (LD ; CM ; CC ; ME ; ED ; AMP ; AE ; JF) ; Université d’Auvergne Clermont 1, Faculté de Pharmacie, Laboratoire de Pharmacologie, Clermont-Ferrand, France (LD ; CC ; ED ; AMP ; JF) ; Université d’Auvergne Clermont 1, Faculté de Médecine, Laboratoire de Pharmacologie Médicale, Clermont-Ferrand, France (CM ; ME ; AE) Molec...

Dermatofibrosarcoma protuberans (DFSP) is a soft tissue tumor with tendency to recur locally and only rarely metastasizes to vital organs. Surgery with wide margins remains the standard treatment. DFSP is characterized by specific chromosomal abnormalities involving the platelet derived growth factor B locus (PDGFB). In the majority of cases a supernumerary ring chromosome containing amplified ...

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous neoplasm associated with a high cure rate. We present a case of aggressive DFSP with fibrosarcomatous areas in the head and neck. A 28-year-old Mediterranean female presented with a 45-day history of rapidly growing cutaneous lesion of the face. Surgical biopsy confirmed the diagnosis of DFSP. Subsequently, the patient underwent wide lo...

68 Correspondence To the Editor: Dermatofibrosarcoma protuberans (DFSP) is a cutaneous soft tissue neoplasm of intermediate-to-low grade malignant potential. It arises from the dermis and invades locally into deeper subcutaneous tissue. It is characterized by a high local recurrence rate after standard surgical excision, partly due to asymmetric infiltration of the subcutis by delicate strands ...

267 simultaneous occurrence with a malignant giant cell tumor of soft parts. Cancer 1993;72:462-8. 3. Morrison AE, Lang PG. Case of rapidly enlarging Dermatofibrosarcoma protuberans during pregnancy followed by metastasis in the absence of local recurrence. Dermatol Surg 2006;32:125-7. 4. Angouridakis N, Kafas P, Jerjes W, et al. Dermatofibrosarcoma protuberans with fibrosarcomatous transformat...

Dermatofibrosarcoma protuberans (DFSP) is a slowly growing dermal spindle cell tumor and its myxoid variant, a rare type of DFSP, is characterized by extensive myxoid degeneration. We present the case of a 69-year-old woman with a multinodular reddish plaque on her trunk. Histopathologically, the tumor was located in the dermis and consisted of uniform spindle-shaped cells, showing strongly pos...