BACKGROUND Asthma and allergic rhinitis affect 15% and 38% of South African (SA) children, respectively. The housedust mite (HDM) is the most significant indoor aeroallergen. Typical HDM species include Dermatophagoides pteronyssinus, D. farinae and Blomia tropicalis. Conventional skin-prick testing (SPT) panels only test for Dermatophagoides. B. tropicalis has been described in the tropical an...

The effect of hyposensitization (HS) upon the allergen evoked immediate asthmatic reaction (IAR), late asthmatic reaction (LAR) and upon bronchial reactivity towards histamine was examined. Eighteen young asthmatic patients were studied using a double-blind, placebo-controlled design. All were allergic to house dust mite (HDM) and demonstrated an IAR and a LAR after bronchial provocation with H...

2 3 4 Validation of a within-trial measure of the oculomotor stop process 5 6 Running head: An empirical measure of the stop signal reaction time 7 8 9 Samanthi C. Goonetilleke, Jeffrey P. Wong, Brian D. Corneil 10 11 Departments of Physiology & Pharmacology, and Psychology, 12 Western University 13 London, Ontario, Canada 14 15 The Brain and Mind Institute 16 Robarts Research Institute 17 Lond...

Background. Allergen-specific immunotherapy (SIT) is one of the important regimens for the treatment of allergic diseases. Predictive tests for the clinical response to SIT are limited. In this study we aimed to evaluate whether specific IgE/total IgE levels can predict clinical improvement in monosensitized patients to house dust mite treated with immunotherapy. Patients and Methods. We analyz...

BACKGROUND Skin tests for specific diagnosis of allergies require high quality extracts, which can be measured by the determination of allergenic potency, utilizing different concentrations of extracts from a manufacturer. OBJETIVE To compare allergenic mite extracts manufactured by laboratories in Spain, Argentina, and Cuba by skin prick test response. METHODS A cutaneous puncture was perf...

PURPOSE Sensitization to house dust mite (Dermatophagoides pteronyssinus) is a considerable risk factor for the progression of allergic disease. The group 2 allergen from Dermatophagoides pteronyssinus, Der p 2, is considered a major one in patients with specific immunoglobulin E (IgE) to Der p 2. Der p 2 has structural homology with myeloid differentiation 2 (MD-2), which is involved in the li...

371 Cutaneous Response to Patch Tests with Dermatophagoides Farinae and Dermatophagoides Pteronyssinus in Patients with Chronic Rhinitis Diego Garcia-Calderin, MD, Sandra González-Díaz, MD, PhD, Alfredo Arias-Cruz, MD, Alejandro Rojas, MD, Marisela Hernandez, MD, Claudia Gallego, MD, Karla Mejia, MD, Maricruz Calva, MD, and Luis Dominguez, MD. Regional Centre of Allergy and Clinical Immunology,...

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus with 12-30% fatality rate. Despite severity of the disease, any medication or treatment for SFTS has not developed yet. One approach to prevent SFTS spreading is to control the arthropod vector carrying SFTS virus. We report that 2-methylbenzaldehyde analogues from M. officinalis have a dua...

Background: Limited publications evaluated the Phadiatop application for aeroallergen screen in allergic respiratory diseases (ARD) Chinese. Our retrospective cohort studied versus total IgE use workups, and local sensitisation profiles by reviewing sIgE. We aimed to derive a cost-effective algorithm ARD workup. Methods: The tests from 694 patients with 2010–2019 were retrospectively identified...