Currently, tumor necrosis factor alpha (TNF-alpha) inhibitors are widely used for many autoimmune disorders. However, they cause an immunocompromised status that sometimes leads to many cutaneous side effects including atypical infections. Herein, we report the first case of adalimumab-related Majocchi's granuloma.A 43-year-old Taiwanese male patient with chronic plaque-type psoriasis developed...

BACKGROUND Onychomycosis is a rare disorder in children. Few studies exist on the incidence or prevalence of onychomycosis in children. OBJECTIVE To examine the epidemiology of childhood onychomycosis in Iceland during the period 1982-2000. METHODS Results from all mycological samples taken from children in Iceland from 1982 to 2000 were examined. Information about the requesting physician,...

Enhancedgene replacements inKu80disruptionmutantsofthe dermatophyte,Trichophytonmentagrophytes Tsuyoshi Yamada, Koichi Makimura, Tatsuya Hisajima, Yumiko Ishihara, Yoshiko Umeda & Shigeru Abe Teikyo University Institute of Medical Mycology, Teikyo University, Tokyo, Japan; Genome Research Center, Teikyo University, Tokyo, Japan; and Department of Alternative Medicine, Faculty of Health Care, Te...

Thirty-two clinical isolates of anthropophlic dermatophytes were examined for their capacity to produce antibiotics in liquid culture and on human stratum corneum in vitro. Antibiotics were detected and classified using agar diffusion bioassays and chromatographic analysis. Twenty-four isolates produced antibiotic substances in liquid culture filtrates; some strains produced more than one antib...

Dermatophytes are the main cause of onychomycoses, but various nondermatophyte filamentous fungi are often isolated from abnormal nails. The correct identification of the aetiological agent of nail infections is necessary in order to recommend appropriate treatment. To evaluate a rapid polymerase chain reaction (PCR) assay based on 28S rDNA for fungal identification in nails on a large number o...

The potential of an electronic nose consisting of a hybrid gas sensor array system has been examined for species discrimination and strain identification of dermatophytes which are causative pathogens for human and animal infection. Temporal volatile production patterns have been studied at a species level for a Microsporum species, two Trichophyton species and at a strain level for the two Tri...

The intergenic spacer (IGS) of the rRNA genes was analyzed from the dermatophyte Trichophyton violaceum isolated from cases of tinea capitis in Taiwan and Iran. T. violaceum strains were cultured from different colonies, from single conidial colonies derived by dilution plating, and from micromanipulation of single conidia from clinical samples. A ribosomal DNA probe hybridizing to multiple Eco...

Dermatophytosis is caused by a dermatophyte fungus that affects the stratum corneum and keratinized tissue. Dermatophyte fungus has been reported worldwide as the causative agent of dermatophytosis, but the etio-epidemiological aspects of these mycoses in the state of Pará remain unknown. The purpose of this study was to describe the etio-epidemiological profile of dermatophytosis diagnosed in ...

PURPOSE To evaluate in-office dermatophyte test medium (DTM) culture as an alternative to traditional laboratory fungal culture for confirming a diagnosis of onychomycosis, and to determine the prevalence of dermatophytes as a cause of onychomycosis in patients not participating in a clinical trial. DESIGN This nationwide multicenter prospective study enrolled 1100 adult patients with suspect...

By means of UV radiation 74 physiological mutants of the dermatophyte Trichophyton mentagrophytes (Robin) Blanchard were induced. These mutants had changed optimum cultivation temperature and mostly changed morphology and sporulation as well.