Access/coverage for anti-obesity medications (AOMs) is limited compared to treatments other chronic diseases, despite high disease burden. We aimed assess the relative value of AOMs through analysis and comparison cost-benefit and/or clinical benefit covered across selected therapeutic areas. Comparators included a single pharmacotherapy per area (smoking cessation, varenicline; daytime sleepin...

The polyamine (PA) was prepared by condensation of 1, 4-bischloromethyl benzene and 1, 4benzene diamine. The PA was then treated with cyanuric chloride at 0oC followed by reaction with sulfanilic acid in THF in concentrated NaOH (pH 9-10) at room temperature for 8 hrs. The resultant polymer designated as polyamine-s-triazine-sulfanilic acid (PATS) was characterized by elemental analysis, IR spe...

We have analyzed the physical origins of the temperature gradient of the ordinary refractive index ( dn(o) /dT) of liquid crystals. To achieve a large dn(o) /dT , high birefringence and low clearing temperature play crucial roles. Based on these simple guidelines, we formulated two exemplary liquid crystal mixtures, designated as UCF-1 and UCF-2, and compared their physical properties with a co...

Adolescence has been typically described as a developmental stage during which risky behaviors are common. Although considerable attention has been paid to high-profile risky behaviors, including alcohol and drug abuse, eating disorders, and smoking, little attention has focused on adolescent problem gambling. Given the DSM criteria of problem gambling being designated as an impulse control dis...

BACKGROUND Cigarette smoke is associated with decreased female fertility, causing damage to ovarian function and disturbing follicle development. However, the effects of cigarette toxicants on ovarian function depend on duration and intensity of exposure. The aim of this study was to assess the effects of brief, intense exposure to tobacco smoke on granulosa cell number, oocyte growth, and foll...

BACKGROUND Smokers with chronic obstructive pulmonary disease (COPD) seem to be a special subgroup of smokers that have a more urgent need to quit smoking but might find it more difficult to do so. This study aimed to explore which justifications for tobacco smoking and experiences of quitting were commonly shared in smokers with and without COPD, and which, if any, were specific to smokers wit...